DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.
about
GSK-3 as potential target for therapeutic intervention in cancerIncreased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformationDNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3beta pathway and activation of caspases.MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signalsHigh susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehydeNovel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.DNA-PK-A candidate driver of hepatocarcinogenesis and tissue biomarker that predicts response to treatment and survival.Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and AktDownregulation of ubiquitin-associated protein 2-like with a short hairpin RNA inhibits human glioma cell growth in vitro.Novel kinase fusion transcripts found in endometrial cancerCommon cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system.Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value.Glycogen synthase kinase 3 beta: can it be a target for oral cancer.The ubiquitin-proteasome system in glioma cell cycle control.Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc ActivitiesThe involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiation.DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress.Clinical significance of inactivated glycogen synthase kinase 3β in HPV-associated cervical cancer: Relationship with Wnt/β-catenin pathway activation.Inhibition of c-Myc expression accounts for an increase in the number of multinucleated cells in human cervical epithelial cells.GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents.Tumor DNA-dependent protein kinase catalytic subunit expression is associated with hepatitis B surface antigen status and tumor progression in patients with hepatocellular carcinoma
P2860
Q27013811-35D36293-3EA8-4C46-846F-E4D2E6880294Q33523235-27876D26-5665-496A-887A-04B32D96B068Q33537400-57030A8A-1FCC-488A-982C-EFD408971DAFQ34053698-2B3442A2-95E8-4C9C-A42A-DD11D35A88B6Q34721752-BAC86889-1581-4FFC-8D37-1BECFA146ECBQ34980645-D891DCB3-24DC-4EBC-86DA-11F874D34A69Q35048652-4F73AB3E-4356-4220-9DA6-8CF8F46AC10BQ35059927-8E71B2A1-3C8E-470D-B3F2-9A61E5EE6F30Q35103519-F5592035-4E63-4F25-B236-DD11B2308B57Q35212557-AA142798-30B1-490F-BB17-20387CFB2B06Q35929017-9E58EFFB-9A4A-4D2E-B6D3-1282E30AA247Q36041696-D1C33330-9BC9-4ADC-ABE5-615194510AE6Q36393068-627D8DF4-5523-4ECE-B00D-11CE0D0E41C3Q36544857-4975C8AD-2E4F-46A8-B1D0-3F09A2B641CBQ36547551-83089493-01EB-4E53-A6C0-0E3FE481D8E4Q36810811-9A5087AC-9D4E-45E8-B5AA-ED2D60C66D0CQ37322983-0BADC7C1-2355-4824-B042-3A52F254CA62Q37764097-62D6EB1B-E7E1-47DD-90B1-81D599B2D5FDQ38028002-50B19C99-DAAC-434D-BA94-9C211511A2F1Q38855197-4845D161-D02E-4832-8B19-A97530FF7119Q38866757-C1769E26-975B-434F-9174-032D5B5B7C9AQ38949833-DE964C2A-44CC-4829-8A38-F48409F4949DQ39012300-AF04831C-BC08-43AA-BF16-8068097D8AC4Q41586966-541D86C5-214F-4D5E-90BF-40A12FFD8FF4Q41600651-E3302371-57F5-4E00-B21A-CED3D8925FA3Q49514489-7222001A-D44C-470D-A7B6-73BC3306B3C0Q57292427-85C0D830-E2A9-46E3-A9F8-3153CD473548
P2860
DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@ast
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@en
type
label
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@ast
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@en
prefLabel
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@ast
DNA-dependent protein kinase c ...... tability of c-Myc oncoprotein.
@en
P2093
P2860
P356
P1433
P1476
DNA-dependent protein kinase c ...... stability of c-Myc oncoprotein
@en
P2093
De-Chang Wu
Dong-Yan Yang
Ping-Kun Zhou
Qin-Zhi Xu
Shi-Meng Zhang
Zeng-Fu Shang
P2860
P2888
P356
10.1186/1476-4598-7-32
P50
P577
2008-04-22T00:00:00Z
P5875
P6179
1051451881