Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice
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β-arrestin1 at the cross-road of endothelin-1 signaling in cancerPromoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant gliomaTreatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel.miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma.Glioblastoma: Defining Tumor Niches.Endothelin therapeutics in cancer: Where are we?Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression.PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signalsThe Microenvironmental Landscape of Brain Tumors.Pharmacotherapeutic Targeting of G Protein-Coupled Receptors in Oncology: Examples of Approved Therapies and Emerging Concepts.Determination of the endothelin-1 recognition sites of endothelin receptor type A by the directed-degeneration method.Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancerExploiting drug repositioning and the brain microenvironment to treat brain metastases.Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells.Macitentan, a double antagonist of endothelin receptors, efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia.Reactive Astrocytes in Brain Metastasis.Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer.Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?[Tumor Cells and Micro-environment in Brain Metastases].Dysregulation of the endothelin pathway in lymphangioleiomyomatosis with no direct effect on cell proliferation and migrationApatinib suppresses cell growth and metastasis and promotes antitumor activity of temozolomide in glioma
P2860
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P2860
Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@ast
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@en
type
label
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@ast
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@en
prefLabel
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@ast
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@en
P2093
P2860
P1476
Macitentan, a Dual Endothelin ...... and Long-term Survival in Mice
@en
P2093
Charles A Conrad
François Lehembre
Ho Jeong Lee
Hyun Jin Choi
Isaiah J Fidler
Kenneth Aldape
Mark Seungwook Kim
Robert R Langley
P2860
P304
P356
10.1158/1078-0432.CCR-14-3195
P407
P577
2015-06-23T00:00:00Z