Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria
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IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusinsMitochondrial glutathione: features, regulation and role in diseaseReactive oxygen species, cellular redox systems, and apoptosisImplications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cellsThe influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue.Use of sodium butyrate as an alternative to dietary fiber: effects on the embryonic development and anti-oxidative capacity of rats.Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis.Degree of glutathione deficiency and redox imbalance depend on subtype of mitochondrial disease and clinical status.Redox control of liver function in health and diseaseALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria.Hydrogen peroxide induces vasorelaxation by enhancing 4-aminopyridine-sensitive Kv currents through S-glutathionylation.Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling.Glutathione and apoptosis.Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by β-phenethyl isothiocyanate: mechanisms for anti-leukemia activity.Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione.Mitochondrial redox studies of oxidative stress in kidneys from diabetic mice.Glutathione homeostasis and functions: potential targets for medical interventionsThe edaravone and 3-n-butylphthalide ring-opening derivative 10b effectively attenuates cerebral ischemia injury in ratsGlutathione and modulation of cell apoptosis.Mitochondrial thiols in the regulation of cell death pathways.Glutathione efflux and cell death.Overexpression of amyloid-β protein precursor induces mitochondrial oxidative stress and activates the intrinsic apoptotic cascadeBcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder.Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress.Interaction between glutathione and apoptosis in systemic lupus erythematosus.The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways.Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiologyMitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cellsBcl-2 family proteins as regulators of oxidative stress.Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis.Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in miceRole of glutathione in cell nucleus.Redox regulation of the intrinsic pathway in neuronal apoptosis.A nuclear glutathione cycle within the cell cycle.Nutraceutical antioxidants as novel neuroprotective agents.Molecular biomarkers of lung carcinoma.Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria.Protective Mechanisms of Flavonoids in Parkinson's Disease.
P2860
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P2860
Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Glutathione binding to the Bcl ...... idant function at mitochondria
@ast
Glutathione binding to the Bcl ...... idant function at mitochondria
@en
type
label
Glutathione binding to the Bcl ...... idant function at mitochondria
@ast
Glutathione binding to the Bcl ...... idant function at mitochondria
@en
prefLabel
Glutathione binding to the Bcl ...... idant function at mitochondria
@ast
Glutathione binding to the Bcl ...... idant function at mitochondria
@en
P2093
P2860
P356
P1476
Glutathione binding to the Bcl ...... idant function at mitochondria
@en
P2093
Angela K Zimmermann
Daniel A Linseman
Emily K Schroeder
F Alexandra Loucks
Ron J Bouchard
P2860
P304
29296-29304
P356
10.1074/JBC.M702853200
P407
P577
2007-08-09T00:00:00Z