Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection.
about
Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogenA comprehensive approach to identification of surface-exposed, outer membrane-spanning proteins of Leptospira interrogans.Global transcriptomic response of Leptospira interrogans serovar Copenhageni upon exposure to serum.In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogansThe terminal immunoglobulin-like repeats of LigA and LigB of Leptospira enhance their binding to gelatin binding domain of fibronectin and host cells.Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectinInduction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogenThe OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin.Establishment of a leptospirosis model in guinea pigs using an epicutaneous inoculations routeFeatures of two proteins of Leptospira interrogans with potential role in host-pathogen interactionsPlasminogen binding proteins and plasmin generation on the surface of Leptospira spp.: the contribution to the bacteria-host interactionsWhole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity.Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis.Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro.Responses of murine and human macrophages to leptospiral infection: a study using comparative array analysis.Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogansEvaluation of cell binding activities of Leptospira ECM adhesins.The novel leptospiral surface adhesin Lsa20 binds laminin and human plasminogen and is probably expressed during infection.The emergence of severe pulmonary hemorrhagic leptospirosis: questions to considerOmpL1 is an extracellular matrix- and plasminogen-interacting protein of Leptospira sppLeptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins.Targeted mutagenesis in pathogenic Leptospira species: disruption of the LigB gene does not affect virulence in animal models of leptospirosis.Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogansProteome analysis of Leptospira interrogans virulent strainCharacterization of three novel adhesins of Leptospira interrogans.Leptospira surface adhesin (Lsa21) induces Toll like receptor 2 and 4 mediated inflammatory responses in macrophages.Reverse Vaccinology: An Approach for Identifying Leptospiral Vaccine Candidates.That's my story, and I'm sticking to it--an update on B. burgdorferi adhesins.Leptospira as an emerging pathogen: a review of its biology, pathogenesis and host immune responsesHuman pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host.Pathogenic, diagnostic and vaccine potential of leptospiral outer membrane proteins (OMPs).Leptospira interrogans binds to human cell surface receptors including proteoglycans.Leptospira interrogans binds to cadherins.Evaluation of two novel leptospiral proteins for their interaction with human host components.Mammalian cell entry (Mce) protein of Leptospira interrogans binds extracellular matrix components, plasminogen and β2 integrin.Evaluation of immunoprotective activity of six leptospiral proteins in the hamster model of leptospirosis.Repeated domains of leptospira immunoglobulin-like proteins interact with elastin and tropoelastin.Plasminogen acquisition and activation at the surface of leptospira species lead to fibronectin degradationDevelopment of transcriptional fusions to assess Leptospira interrogans promoter activity.
P2860
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P2860
Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Lsa21, a novel leptospiral pro ...... resent during human infection.
@ast
Lsa21, a novel leptospiral pro ...... resent during human infection.
@en
type
label
Lsa21, a novel leptospiral pro ...... resent during human infection.
@ast
Lsa21, a novel leptospiral pro ...... resent during human infection.
@en
prefLabel
Lsa21, a novel leptospiral pro ...... resent during human infection.
@ast
Lsa21, a novel leptospiral pro ...... resent during human infection.
@en
P2093
P2860
P50
P356
P1433
P1476
Lsa21, a novel leptospiral pro ...... present during human infection
@en
P2093
Dirce Mc Lima
Marina V Atzingen
Silvio A Vasconcellos
Thales De Brito
Zenáide M de Morais
P2860
P2888
P356
10.1186/1471-2180-8-70
P577
2008-04-29T00:00:00Z