A segment of 97 amino acids within the translocation domain of Clostridium difficile toxin B is essential for toxicity
about
Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore.Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region.Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides.Defective mutations within the translocation domain of Clostridium difficile toxin B impair disease pathogenesis.Identification of an Essential Region for Translocation of Clostridium difficile Toxin B.Immune-based treatment and prevention of Clostridium difficile infection.Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.Amino Acid Differences in the 1753-to-1851 Region of TcdB Influence Variations in TcdB1 and TcdB2 Cell Entry.A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.The role of purified Clostridium difficile glucosylating toxins in disease pathogenesis utilizing a murine cecum injection model.Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin.Receptors and Binding Structures for Clostridium difficile Toxins A and B.Novel Chimeric Protein Vaccines Against Infection
P2860
Q34406643-1E570016-4135-48AC-9FC3-A992A03E8B9DQ34955649-8F2C8D59-6E1D-404D-8F28-5CFEE72E3180Q35172641-7A21FE98-5DF4-4E72-98B6-28C7C4E38618Q35591558-4A4B0B83-BF4A-4487-9323-9B00273A5994Q36940225-02DEEC63-E90C-4FA1-86C0-B245D26708D2Q37209035-ABFE242C-7ED0-4637-BB88-F55762C2A57DQ38350907-58E6E1EE-6A52-44B3-A7E2-D0D56566B491Q38682995-BBEAAD10-D61D-4E24-BBF6-91E173BE08DFQ41223672-05299B35-5D76-47E6-8086-D8A4C155F0F4Q47694597-A8AA723F-A1CB-4774-B569-E15C172DF006Q49282081-EB00AB25-726A-42ED-906E-3C5938309776Q49790754-3B2A0BE4-DE6E-49B8-A7F6-EB3726501E7CQ51662356-DB9E4D54-C0FD-4772-ACFA-6115D52C92E9Q58580396-6854F4F9-C164-4B0F-AC40-5E804E291D34
P2860
A segment of 97 amino acids within the translocation domain of Clostridium difficile toxin B is essential for toxicity
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A segment of 97 amino acids wi ...... in B is essential for toxicity
@ast
A segment of 97 amino acids wi ...... in B is essential for toxicity
@en
type
label
A segment of 97 amino acids wi ...... in B is essential for toxicity
@ast
A segment of 97 amino acids wi ...... in B is essential for toxicity
@en
prefLabel
A segment of 97 amino acids wi ...... in B is essential for toxicity
@ast
A segment of 97 amino acids wi ...... in B is essential for toxicity
@en
P2093
P2860
P1433
P1476
A segment of 97 amino acids wi ...... in B is essential for toxicity
@en
P2093
Clive Standley
Hanping Feng
Lianfa Shi
Ronghua ZhuGe
Tor Savidge
Xiaoning Wang
Zhiyong Yang
Zhong Yang
P2860
P304
P356
10.1371/JOURNAL.PONE.0058634
P407
P577
2013-03-06T00:00:00Z