DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage. - Wikidata - wikimedia - TriplyDB

DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

http://www.wikidata.org/entity/Q36663129

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Mechanisms underlying structural variant formation in genomic disorders Noncanonical views of homology-directed DNA repair Rescue from replication stress during mitosis.Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells.Mechanisms for Complex Chromosomal Insertions.RPA Stabilization of Single-Stranded DNA Is Critical for Break-Induced Replication.A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination.Mechanisms for the Generation of Two Quadruplications Associated with Split-Hand Malformation Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation.Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains.Stalled replication forks generate a distinct mutational signature in yeast.Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement.Break-induced telomere synthesis underlies alternative telomere maintenance.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Consider the workhorse: Nonhomologous end-joining in budding yeast.The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks.Non-Canonical Replication Initiation: You're Fired!Break-induced replication: an unhealthy choice for stress relief?Whole-Genome Sequencing of Cytogenetically Balanced Chromosome Translocations Identifies Potentially Pathological Gene Disruptions and Highlights the Importance of Microhomology in the Mechanism of Formation.Break-induced replication links microsatellite expansion to complex genome rearrangements.Role of recombination and replication fork restart in repeat instability.Precarious maintenance of simple DNA repeats in eukaryotes.SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.POLD3 Is Haploinsufficient for DNA Replication in Mice.The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats.Remarkably Long-Tract Gene Conversion Induced by Fragile Site Instability in Saccharomyces cerevisiae.Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus.Nonrecurrent PMP22-RAI1 contiguous gene deletions arise from replication-based mechanisms and result in Smith-Magenis syndrome with evident peripheral neuropathy.Role of PCNA and RFC in promoting Mus81-complex activity.Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication.The SMX DNA Repair Tri-nuclease.Multi-invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements.The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks.53BP1 and BRCA1 control pathway choice for stalled replication restart.WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome.Mechanism of tandem duplication formation in BRCA1-mutant cells.Oxygen and RNA in stress-induced mutation.Break induced replication in eukaryotes: mechanisms, functions, and consequences.

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DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

http://www.wikidata.org/entity/Q36663129

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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DNA REPAIR. Mus81 and convergi ...... of replication fork breakage.

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SCIENCE.AAA8391

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DNA REPAIR. Mus81 and convergi ...... y of replication fork breakage

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Chad A Shaw

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Christine R Beck

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Grzegorz Ira

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James R Lupski

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Lotte Bjergbaek

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Ryan Mayle

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Yang Yu

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P2860

Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae.

Migrating bubble during break-induced replication drives conservative DNA synthesis.

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

Break-induced replication repair of damaged forks induces genomic duplications in human cells.

Break-induced replication is highly inaccurate

The Alu-rich genomic architecture of SPAST predisposes to diverse and functionally distinct disease-associated CNV alleles.

Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.

Break-induced replication is a source of mutation clusters underlying kataegis

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3.

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742-747

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6249

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Ian M. Campbell

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26273056

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