Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation - Wikidata - wikimedia - TriplyDB

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

http://www.wikidata.org/entity/Q36666804

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Transcriptional Regulation of Mononuclear Phagocyte Development Molecular control of monocyte development Distinct dendritic cell subsets actively induce Th2 polarization Nonclassical patrolling monocyte function in the vasculature The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages.Epigenomics of macrophages.Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes.Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection.In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis.MMP3-mediated tumor progression is controlled transcriptionally by a novel IRF8-MMP3 interaction.3,3'-Diindolylmethane Inhibits Flt3L/GM-CSF-induced-bone Marrow-derived CD103(+) Dendritic Cell Differentiation Regulating Phosphorylation of STAT3 and STAT5.The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis.Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.Transcriptional Control of Dendritic Cell Development.Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development.Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.Transcription factor Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate.From proliferation to proliferation: monocyte lineage comes full circle.Functions and development of red pulp macrophages.Regulation of myelopoiesis by the transcription factor IRF8.Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species?Reprogramming of histone methylation controls the differentiation of monocytes into macrophages.Role of the reprogramming factor KLF4 in blood formation.Krüppel-like factors in mammalian stem cells and development.Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes P2 receptors, microglial cytokines and chemokines, and neuropathic pain.2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.Discovering sparse transcription factor codes for cell states and state transitions during development Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio.Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.Functions of Murine Dendritic Cells.Mechanisms overseeing myeloid-derived suppressor cell production in neoplastic disease.Krüppel-like factor 4 (KLF4): What we currently know.Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex.

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Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

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Essential role of the IRF8-KLF ...... urine monocyte differentiation

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Daisuke Kurotaki

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Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

Blood monocytes: development, heterogeneity, and relationship with dendritic cells

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

ICSBP/IRF-8: its regulatory roles in the development of myeloid cells

Histone modifications at human enhancers reflect global cell-type-specific gene expression

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

Blood monocytes consist of two principal subsets with distinct migratory properties

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