Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis.
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Shutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesDevelopment of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genesInfluenza a virus host shutoff disables antiviral stress-induced translation arrestPolymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cellsThe contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses.Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune ResponsesTwenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity.Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low TemperaturesResidues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses.Generation and Comprehensive Analysis of Host Cell Interactome of the PA Protein of the Highly Pathogenic H5N1 Avian Influenza Virus in Mammalian CellsPA-X decreases the pathogenicity of highly pathogenic H5N1 influenza A virus in avian species by inhibiting virus replication and host response.A complete map of potential pathogenicity markers of avian influenza virus subtype H5 predicted from 11 expressed proteinsEquine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence.Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.Identification of combinatorial host-specific signatures with a potential to affect host adaptation in influenza A H1N1 and H3N2 subtypes.N-Terminal Domain of Feline Calicivirus (FCV) Proteinase-Polymerase Contributes to the Inhibition of Host Cell Transcription.Critical Role of the PA-X C-Terminal Domain of Influenza A Virus in Its Subcellular Localization and Shutoff ActivityAmino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.Crucial role of PA in virus life cycle and host adaptation of influenza A virus.Emerging roles for RNA degradation in viral replication and antiviral defense.Timing Is Everything: Coordinated Control of Host Shutoff by Influenza A Virus NS1 and PA-X Proteins.Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression.Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution.Histone Deacetylase 2 Is a Component of Influenza A Virus-Induced Host Antiviral Response.PA-X-associated early alleviation of the acute lung injury contributes to the attenuation of a highly pathogenic H5N1 avian influenza virus in mice.Mapping of a Region of the PA-X Protein of Influenza A Virus That Is Important for Its Shutoff Activity.The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA.Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3.Impact of influenza PA-X on host response.Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in HumansHost Shutoff in Influenza A Virus: Many Means to an End
P2860
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P2860
Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Identification of the N-termin ...... ion of host protein synthesis.
@ast
Identification of the N-termin ...... ion of host protein synthesis.
@en
type
label
Identification of the N-termin ...... ion of host protein synthesis.
@ast
Identification of the N-termin ...... ion of host protein synthesis.
@en
prefLabel
Identification of the N-termin ...... ion of host protein synthesis.
@ast
Identification of the N-termin ...... ion of host protein synthesis.
@en
P2093
P2860
P356
P1433
P1476
Identification of the N-termin ...... sion of host protein synthesis
@en
P2093
Emily A Desmet
Raychel Stone
Toru Takimoto
P2860
P304
P356
10.1128/JVI.02826-12
P407
P577
2013-01-02T00:00:00Z