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The ageing cortical synapse: hallmarks and implications for cognitive decline

The ageing cortical synapse: hallmarks and implications for cognitive decline

http://www.wikidata.org/entity/Q36668062

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The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course Age-associated Cognitive Decline: Insights into Molecular Switches and Recovery Avenues NMDA Receptor Function During Senescence: Implication on Cognitive Performance The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease Postmenopausal hormone therapy and cognition Aging in the olfactory system Molecular aspects of age-related cognitive decline: the role of GABA signaling Learning and memory Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults.Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release Current automated 3D cell detection methods are not a suitable replacement for manual stereologic cell counting Age and the metabolic syndrome as risk factors for ischemic stroke: improving preclinical models of ischemic stroke Increased axonal bouton dynamics in the aging mouse cortex Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?Studying synapses in human brain with array tomography and electron microscopy Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.Diminished KCC2 confounds synapse specificity of LTP during senescence Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease Enhanced performance of aged rats in contingency degradation and instrumental extinction tasks.Adrenocortical status predicts the degree of age-related deficits in prefrontal structural plasticity and working memory.Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease.Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging.Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice.Communication breakdown: the impact of ageing on synapse structure.Simultaneous changes of spatial memory and spine density after intrahippocampal administration of fibrillar aβ1-42 to the rat brain Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity Differential effects of aging on dendritic spines in visual cortex and prefrontal cortex of the rhesus monkey.Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.Successful brain aging: plasticity, environmental enrichment, and lifestyle.Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.Aging and brain rejuvenation as systemic events.Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse Negative neuroplasticity in chronic traumatic brain injury and implications for neurorehabilitation Textrous!: extracting semantic textual meaning from gene sets.SynPAnal: software for rapid quantification of the density and intensity of protein puncta from fluorescence microscopy images of neurons.Mobile technologies in the early detection of cognitive decline.Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering.Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons.

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The ageing cortical synapse: hallmarks and implications for cognitive decline

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The ageing cortical synapse: hallmarks and implications for cognitive decline

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The ageing cortical synapse: hallmarks and implications for cognitive decline

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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Dynamic Network Connectivity: A new form of neuroplasticity

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

Estrogen and cognitive functioning in women: lessons we have learned

Structure-stability-function relationships of dendritic spines

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide

Regulation of NMDA receptor trafficking by amyloid-beta

Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons

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