The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
about
The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegansInflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyreneAssessing the impact of Benzo[a]pyrene on Marine Mussels: Application of a novel targeted low density microarray complementing classical biomarker responsesEffect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways.Metabolic activation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and DNA adduct formation depends on p53: Studies in Trp53(+/+),Trp53(+/-) and Trp53(-/-) miceTranscriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene.Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation.Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems.Genotoxicity of fine and coarse fraction ambient particulate matter in immortalised normal (TT1) and cancer-derived (A549) alveolar epithelial cells.Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.Potent mutagenicity of some non-planar tri- and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme.
P2860
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P2860
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@ast
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@en
type
label
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@ast
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@en
prefLabel
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@ast
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@en
P2093
P2860
P50
P1476
The impact of p53 on DNA damag ...... Trp53(+/-) and Trp53(-/-) mice
@en
P2093
Albrecht Seidel
Annette M Krais
Ewoud N Speksnijder
Frederik-J van Schooten
Heinz H Schmeiser
Joost P M Melis
Klaus Kopka
Mirjam Luijten
Roger W Godschalk
Volker M Arlt
P2860
P2888
P304
P356
10.1007/S00204-015-1531-8
P577
2015-05-21T00:00:00Z