Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family
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Regulators of Slc4 bicarbonate transporter activityIrbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in miceMechanism and synergism in epithelial fluid and electrolyte secretion.cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism.NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease.The ethanol-induced stimulation of rat duodenal mucosal bicarbonate secretion in vivo is critically dependent on luminal Cl-Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters.Short-term regulation of murine colonic NBCe1-B (electrogenic Na+/HCO3(-) cotransporter) membrane expression and activity by protein kinase C.IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues.Cation-coupled bicarbonate transportersAhcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association.Governing effect of regulatory proteins for Cl(-)/HCO3(-) exchanger 2 activity.Hypertension: the missing WNKs.Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis.Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO3 (-) cotransporter NBCe1Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties.A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity.TGF-β signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes.Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport.The Ste20 kinases SPAK and OSR1 travel between cells through exosomes.Lipids at membrane contact sites: cell signaling and ion transport.Regulation of functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), in mouse astrocytes.Phosphatidylinositol 4,5-bisphosphate degradation inhibits the Na+/bicarbonate cotransporter NBCe1-B and -C variants expressed in Xenopus oocytes.The IP3 R Binding Protein Released With Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa.WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers.Nanomaterials-Based Approaches for the Modulation of Sodium Bicarbonate Cotransporters
P2860
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P2860
Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@ast
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@en
type
label
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@ast
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@en
prefLabel
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@ast
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@en
P2093
P2860
P356
P1476
Convergence of IRBIT, phosphat ...... a+-HCO3- cotransporters family
@en
P2093
Dongki Yang
Ehud Ohana
Jeong Hee Hong
Nikolay Shcheynikov
Shmuel Muallem
P2860
P304
P356
10.1073/PNAS.1221410110
P407
P577
2013-02-19T00:00:00Z