A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter.
about
Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RBHomeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.DDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FA cellular repressor of E1A-stimulated genes that inhibits activation by E2FCell cycle-regulated expression of mammalian CDC6 is dependent on E2F.Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.Use of chromatin immunoprecipitation to clone novel E2F target promotersCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseE2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycleCyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylationThe subcellular localization of E2F-4 is cell-cycle dependentExpression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factorCell cycle-regulated association of E2F1 and Sp1 is related to their functional interactionIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionDifferential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteinsE2F-5, a new E2F family member that interacts with p130 in vivoSubcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscleAccumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21Identification of a novel E1A response element in the mouse c-fos promoter.E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytesDisruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis.A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sitesThe J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.Regulation of cellular genes in a chromosomal context by the retinoblastoma tumor suppressor proteinLack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.Target gene specificity of E2F and pocket protein family members in living cells.Characterization of the deoxycytidine kinase promoter in human lymphoblast cell linesDeficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.Inhibition of TFII-I-dependent cell cycle regulation by p53.The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP.A mathematical model of the folate cycle: new insights into folate homeostasis.Characterization of cis-regulatory elements of the c-myc promoter responding to human GM-CSF or mouse interleukin 3 in mouse proB cell line BA/F3 cells expressing the human GM-CSF receptorDistinct roles of E2F recognition sites as positive or negative elements in regulation of the DNA polymerase alpha 180 kDa catalytic subunit gene promoter during Drosophila development.p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes.Transcriptional regulation of the dihydrofolate reductase gene.Identification of a 68 kDa protein species as a specific DNA-binding component of the H3abp complex interacting with the histone H3.2 G1/S regulatory domain.Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivoExpression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression
P2860
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P2860
A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@ast
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@en
type
label
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@ast
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@en
prefLabel
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@ast
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@en
P2093
P2860
P356
P1476
A protein synthesis-dependent ...... ydrofolate reductase promoter.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.3.1610
P407
P577
1993-03-01T00:00:00Z