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Perturbational profiling of nanomaterial biologic activity

Perturbational profiling of nanomaterial biologic activity

http://www.wikidata.org/entity/Q36677215

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Nanotechnology, nanotoxicology, and neuroscience Nanoparticle-based monitoring of cell therapy.The biomechanisms of metal and metal-oxide nanoparticles' interactions with cells Chemical basis of interactions between engineered nanoparticles and biological systems No time to lose--high throughput screening to assess nanomaterial safety Relating Nanoparticle Properties to Biological Outcomes in Exposure Escalation Experiments Quantitative nanostructure-activity relationship modeling Nanoinformatics: a new area of research in nanomedicine Engineered nanomaterials: exposures, hazards, and risk prevention A 21st century paradigm for evaluating the health hazards of nanoscale materials?Nanomaterials toxicity and cell death modalities Susceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strains Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle.Current situation on the availability of nanostructure-biological activity data.The toxicity data landscape for environmental chemicals.Rapid detection and profiling of cancer cells in fine-needle aspirates.Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.Hierarchical Rank Aggregation with Applications to Nanotoxicology.Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots.Classification NanoSAR development for cytotoxicity of metal oxide nanoparticles TOXICITY PROFILING OF ENGINEERED NANOMATERIALS VIA MULTIVARIATE DOSE-RESPONSE SURFACE MODELING.Metal-based nanoparticles and their toxicity assessment.Manufacture of IRDye800CW-coupled Fe3O4 nanoparticles and their applications in cell labeling and in vivo imaging.Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier.Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.A core-shell nanomaterial with endogenous therapeutic and diagnostic functions.NanoParticle Ontology for cancer nanotechnology research.Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays.Gold nanoparticles administration induced prominent inflammatory, central vein intima disruption, fatty change and Kupffer cells hyperplasia The appearance of renal cells cytoplasmic degeneration and nuclear destruction might be an indication of GNPs toxicity.A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting Renal tissue alterations were size-dependent with smaller ones induced more effects and related with time exposure of gold nanoparticles.Gold nanoparticles induced cloudy swelling to hydropic degeneration, cytoplasmic hyaline vacuolation, polymorphism, binucleation, karyopyknosis, karyolysis, karyorrhexis and necrosis in the liver Determination of the surface density of polyethylene glycol on gold nanoparticles by use of microscale thermogravimetric analysis.Histological alterations in the liver of rats induced by different gold nanoparticle sizes, doses and exposure duration.Nanoparticle-mediated measurement of target-drug binding in cancer cells Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5.Multimodal iron oxide nanoparticles for hybrid biomedical imaging.

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P2860

Perturbational profiling of nanomaterial biologic activity

http://www.wikidata.org/entity/Q36677215

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Perturbational profiling of nanomaterial biologic activity

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Perturbational profiling of nanomaterial biologic activity

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Proceedings of the National Academy of Sciences of the United States of America

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Perturbational profiling of nanomaterial biologic activity

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Aravind Subramanian

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Elizabeth C Westly

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Mikael J Pittet

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Stanley Y Shaw

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Stuart L Schreiber

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P2860

Targeting quantum dots to surface proteins in living cells with biotin ligase.

Quantum dots for live cells, in vivo imaging, and diagnostics

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats

Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation

GenePattern 2.0

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

Oops they did it again! Carbon nanotubes hoax scientists in viability assays

Immunological properties of engineered nanomaterials

Safe handling of nanotechnology

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Ralph Weissleder

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