A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans
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The kinase domains of obscurin interact with intercellular adhesion proteinsThe SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle.Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistanceMolecular structure of sarcomere-to-membrane attachment at M-Lines in C. elegans muscleObscure functions: the location-function relationship of obscurins.Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.Muscle giants: molecular scaffolds in sarcomerogenesis.The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viabilityTwitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle.Bending amplitude - a new quantitative assay of C. elegans locomotion: identification of phenotypes for mutants in genes encoding muscle focal adhesion componentsUNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans.A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites.α-actinin is required for the proper assembly of Z-disk/focal-adhesion-like structures and for efficient locomotion in Caenorhabditis elegans.The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila.CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegansZYX-1, the unique zyxin protein of Caenorhabditis elegans, is involved in dystrophin-dependent muscle degenerationThe DH-PH region of the giant protein UNC-89 activates RHO-1 GTPase in Caenorhabditis elegans body wall muscleCSN-5, a component of the COP9 signalosome complex, regulates the levels of UNC-96 and UNC-98, two components of M-lines in Caenorhabditis elegans muscle.Obscurins: unassuming giants enter the spotlight.Mechanistic and functional diversity in the mechanosensory kinases of the titin-like family.Structure of giant muscle proteins.An approach for exploring interaction between two proteins in vivoThe sarcomeric M-region: a molecular command center for diverse cellular processes.Obscurin depletion impairs organization of skeletal muscle in developing zebrafish embryos.Binding partners of the kinase domains in Drosophila obscurin and their effect on the structure of the flight muscle.Twitchin kinase inhibits muscle activity.Immunofluorescent localization of proteins in Caenorhabditis elegans muscle.Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.The potential of obscurin as a therapeutic target in muscle disorders.
P2860
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P2860
A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@ast
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@en
type
label
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@ast
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@en
prefLabel
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@ast
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@en
P2093
P2860
P356
P1476
A novel protein phosphatase is ...... rin) in Caenorhabditis elegans
@en
P2093
Guy M Benian
Hiroshi Qadota
Kristina B Mercer
Lee Anne McGaha
Thomas J Stark
Tracey M Ferrara
P2860
P304
P356
10.1091/MBC.E08-01-0053
P577
2008-03-12T00:00:00Z