Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.
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Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesisProtein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with DysregulationEnhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia.Developing an irreversible inhibitor of human DDAH-1, an enzyme upregulated in melanoma.Chemical biology of protein arginine modifications in epigenetic regulationExtracellular traps and macrophages: new roles for the versatile phagocyte.Peptidylarginine Deiminase Inhibitor Suppresses Neutrophil Extracellular Trap Formation and MPO-ANCA ProductionCitrullination of glial intermediate filaments is an early response in retinal injuryModulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway.Chemical and biological methods to detect post-translational modifications of arginine.Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivationCitrullination and carbamylation in the pathophysiology of rheumatoid arthritis.Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous SystemMyelin Basic Protein Citrullination in Multiple Sclerosis: A Potential Therapeutic Target for the Pathology.2-Chloroacetamidine, a novel immunomodulator, suppresses antigen-induced mouse airway inflammation.Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?Interrogation of the Active Sites of Protein Arginine Deiminases (PAD1, -2, and -4) Using Designer ProbesMyelin Basic Protein Citrullination, a Hallmark of Central Nervous System Demyelination, Assessed by Novel Monoclonal Antibodies in Prion Diseases.The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells.Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.And Yet it is Modified-Holding a Candle to the Dark Matter of White Matter.Human Deiminases: Isoforms, Substrate Specificities, Kinetics, and Detection.Biochemically altered myelin triggers autoimmune demyelination
P2860
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P2860
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@ast
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@en
type
label
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@ast
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@en
prefLabel
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@ast
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@en
P2093
P2860
P356
P1476
Inhibition of peptidyl-arginin ...... models of multiple sclerosis.
@en
P2093
Cameron Ackerley
D Denise Wood
Fabrizio G Mastronardi
Helena Lei
Hubert Tsui
Mario A Moscarello
Shawn Winer
P2860
P304
P356
10.1242/DMM.010520
P577
2012-11-01T00:00:00Z