Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency.
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Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients.Contribution of Recombination to the Evolution of Human Immunodeficiency Viruses Expressing Resistance to Antiretroviral TreatmentCytidine deamination induced HIV-1 drug resistanceHuman immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integrationAccurately measuring recombination between closely related HIV-1 genomesProbing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analysesMultiple nucleotide preferences determine cleavage-site recognition by the HIV-1 and M-MuLV RNases H.Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication.A novel molecular mechanism of dual resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors.APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms.Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excisionMechanism analysis indicates that recombination events in HIV-1 initiate and complete over short distances, explaining why recombination frequencies are similar in different sections of the genomeComparison of the genetic recombination rates of human immunodeficiency virus type 1 in macrophages and T cellsThe Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance.N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation.Retroviral vectors for analysis of viral mutagenesis and recombination.The "Connection" Between HIV Drug Resistance and RNase HDimeric RNA recognition regulates HIV-1 genome packaging.Evolution and recombination of genes encoding HIV-1 drug resistance and tropism during antiretroviral therapyMechanisms and factors that influence high frequency retroviral recombinationMutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistanceA Novel Leu92 Mutant of HIV-1 Reverse Transcriptase with a Selective Deficiency in Strand Transfer Causes a Loss of Viral Replication.Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance.Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment.Subunit-selective mutational analysis and tissue culture evaluations of the interactions of the E138K and M184I mutations in HIV-1 reverse transcriptase.Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients.Recombination between variants from genital tract and plasma: evolution of multidrug-resistant HIV type 1Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitorsApparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.Analysis of HIV-1 intersubtype recombination breakpoints suggests region with high pairing probability may be a more fundamental factor than sequence similarity affecting HIV-1 recombinationThe remarkable frequency of human immunodeficiency virus type 1 genetic recombinationPreferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases HHost SAMHD1 protein promotes HIV-1 recombination in macrophages.Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer.Fifteen to twenty percent of HIV substitution mutations are associated with recombinationAltered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis.Pseudodiploid genome organization AIDS full-length human immunodeficiency virus type 1 DNA synthesis.Latent HIV-1 can be reactivated by cellular superinfection in a Tat-dependent manner, which can lead to the emergence of multidrug-resistant recombinant viruses.Recombination in feline lentiviral genomes during experimental cross-species infection.
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P2860
Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Antiretroviral drug resistance ...... template-switching frequency.
@ast
Antiretroviral drug resistance ...... template-switching frequency.
@en
type
label
Antiretroviral drug resistance ...... template-switching frequency.
@ast
Antiretroviral drug resistance ...... template-switching frequency.
@en
prefLabel
Antiretroviral drug resistance ...... template-switching frequency.
@ast
Antiretroviral drug resistance ...... template-switching frequency.
@en
P2093
P2860
P1433
P1476
Antiretroviral drug resistance ...... template-switching frequency.
@en
P2093
Evguenia S Svarovskaia
Galina N Nikolenko
Krista A Delviks
Vinay K Pathak
P2860
P304
P356
10.1128/JVI.78.16.8761-8770.2004
P407
P577
2004-08-01T00:00:00Z