Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.
about
Fibroblasts, an inconspicuous but essential player in colon cancer development and progressionGFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer.Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In VitroArctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapyTumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways.Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination StudiesInhibition of glycogen synthase kinase 3 beta (GSK3β) suppresses the progression of esophageal squamous cell carcinoma by modifying STAT3 activity.NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer.Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology.Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation.Interleukin 6 Present in Inflammatory Ascites from Advanced Epithelial Ovarian Cancer Patients Promotes Tumor Necrosis Factor Receptor 2-Expressing Regulatory T Cells.G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.Targeting tumor microenvironment to curb chemoresistance via novel drug delivery strategies.Dihydroartemisinin increases apoptosis of colon cancer cells through targeting Janus kinase 2/signal transducer and activator of transcription 3 signaling.Inflammation and Colorectal Cancer.Cancer-associated fibroblasts induce cancer cell apoptosis that regulates invasion mode of tumours.Modeling Stroma-Induced Drug Resistance in a Tissue-Engineered Tumor Model of Ewing Sarcoma.Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells.FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition.IGF-1-induced MMP-11 expression promotes the proliferation and invasion of gastric cancer cells through the JAK1/STAT3 signaling pathway.Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis.Coexpression of p-IGF-1R and MMP-7 Modulates Panitumumab and Cetuximab Efficacy in RAS Wild-Type Metastatic Colorectal Cancer Patients.Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.
P2860
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P2860
Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@ast
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@en
type
label
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@ast
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@en
prefLabel
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@ast
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@en
P2093
P2860
P356
P1433
P1476
Targeting colorectal cancer vi ...... substrate and STAT3 signaling.
@en
P2093
A Levitzki
E Flashner-Abramson
K Taniguchi
S Shalapour
P2860
P2888
P304
P356
10.1038/ONC.2015.326
P407
P577
2015-09-14T00:00:00Z