Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution.
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A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting proteinModeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimerDNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational SimulationsDifferential modulation of functional dynamics and allosteric interactions in the Hsp90-cochaperone complexes with p23 and Aha1: a computational study.Allosteric regulation of the Hsp90 dynamics and stability by client recruiter cochaperones: protein structure network modelingComputational modeling of allosteric regulation in the hsp90 chaperones: a statistical ensemble analysis of protein structure networks and allosteric communications.Predicting interaction sites from the energetics of isolated proteins: a new approach to epitope mapping.Paths of long-range communication in the E2 enzymes of family 3: a molecular dynamics investigation.ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.Methionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.Using simulations to provide the framework for experimental protein folding studiesProbing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.Molecular and thermodynamic insights into the conformational transitions of Hsp90.Capture and quality control mechanisms for adenosine-5'-triphosphate binding.Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitorsConformational dynamics of the molecular chaperone Hsp90Molecular dynamics simulations of hsp90 with an eye to inhibitor design.An interdomain sector mediating allostery in Hsp70 molecular chaperones.Force distribution reveals signal transduction in E. coli Hsp90.Structural bioinformatics and protein docking analysis of the molecular chaperone-kinase interactions: towards allosteric inhibition of protein kinases by targeting the hsp90-cdc37 chaperone machinery.Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.Fluoride Alters Klk4 Expression in Maturation Ameloblasts through Androgen and Progesterone Receptor Signaling.Computational Modeling of the Hsp90 Interactions with Cochaperones and Small-Molecule Inhibitors.Functional annotation of the mesophilic-like character of mutants in a cold-adapted enzyme by self-organising map analysis of their molecular dynamics.
P2860
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P2860
Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Understanding ligand-based mod ...... dynamics at atomic resolution.
@ast
Understanding ligand-based mod ...... dynamics at atomic resolution.
@en
type
label
Understanding ligand-based mod ...... dynamics at atomic resolution.
@ast
Understanding ligand-based mod ...... dynamics at atomic resolution.
@en
prefLabel
Understanding ligand-based mod ...... dynamics at atomic resolution.
@ast
Understanding ligand-based mod ...... dynamics at atomic resolution.
@en
P2093
P2860
P356
P1476
Understanding ligand-based mod ...... dynamics at atomic resolution.
@en
P2093
Gennady Verkhivker
Giorgio Colombo
Giulia Morra
Massimiliano Meli
P2860
P304
P356
10.1073/PNAS.0802879105
P407
P577
2008-05-29T00:00:00Z