Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.
about
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingAdenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases.Role of middle T-small T in the lytic cycle of polyomavirus: control of the early-to-late transcriptional switch and viral DNA replicationNatural biology of polyomavirus middle T antigen.Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity.Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans.Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A.Amino-terminal regions of polyomavirus middle T antigen are required for interactions with protein phosphatase 2A.Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A.pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence.Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells
P2860
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P2860
Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Mutation of a cysteine residue ...... , and cellular transformation.
@ast
Mutation of a cysteine residue ...... , and cellular transformation.
@en
type
label
Mutation of a cysteine residue ...... , and cellular transformation.
@ast
Mutation of a cysteine residue ...... , and cellular transformation.
@en
prefLabel
Mutation of a cysteine residue ...... , and cellular transformation.
@ast
Mutation of a cysteine residue ...... , and cellular transformation.
@en
P2860
P1433
P1476
Mutation of a cysteine residue ...... n, and cellular transformation
@en
P2093
P2860
P304
P407
P577
1993-04-01T00:00:00Z