An enhancer/locus control region is not sufficient to open chromatin.
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BEST1 expression in the retinal pigment epithelium is modulated by OTX family membersGenome-wide identification of DNaseI hypersensitive sites using active chromatin sequence librariesLocus control regionsThe locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells.The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes.Structural and functional cross-talk between a distant enhancer and the epsilon-globin gene promoter shows interdependence of the two elements in chromatin.Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy.Function of the upstream hypersensitive sites of the chicken beta-globin gene cluster in mice.Beta-globin locus control region HS2 and HS3 interact structurally and functionallySp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.The 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice.Life without white fat: a transgenic mouseThe beta-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cellsGammaretroviral vector integration occurs overwhelmingly within and near DNase hypersensitive sitesA dominant chromatin-opening activity in 5' hypersensitive site 3 of the human beta-globin locus control region.Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenesA large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice.Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha geneA novel element upstream of the Vgamma2 gene in the murine T cell receptor gamma locus cooperates with the 3' enhancer to act as a locus control region.A novel cis-acting centromeric DNA element affects S. pombe centromeric chromatin structure at a distance.Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control regionExpression of the chicken beta-globin gene cluster in mice: correct developmental expression and distributed control.Regulation of the myeloid-cell-expressed human gp91-phox gene as studied by transfer of yeast artificial chromosome clones into embryonic stem cells: suppression of a variegated cellular pattern of expression requires a full complement of distant ciDistal enhancer regulation by promoter derepression in topologically constrained DNA in vitro.Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element.Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic miceRIGS (repeat-induced gene silencing) in Arabidopsis is transcriptional and alters chromatin configuration.A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation.Discovery of functional noncoding elements by digital analysis of chromatin structure.Chromatin structure and transcriptional control elements of the erythroid Krüppel-like factor (EKLF) gene.In vivo regulation of murine granzyme B gene transcription in activated primary T cells.The effect of matrix attached regions (MAR) and specialized chromatin structure (SCS) on the expression of gene constructs in cultured cells and in transgenic mice.Chromatin structure and gene expressionRole of NF-Y in in vivo regulation of the gamma-globin geneThe developmental activation of the chicken lysozyme locus in transgenic mice requires the interaction of a subset of enhancer elements with the promoterSheltering of gamma-globin expression from position effects requires both an upstream locus control region and a regulatory element 3' to the A gamma-globin geneThe bulk chromatin structure of a murine transgene does not vary with its transcriptional or DNA methylation status.Chromosomal position effects in chicken lysozyme gene transgenic mice are correlated with suppression of DNase I hypersensitive site formation.Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice.
P2860
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P2860
An enhancer/locus control region is not sufficient to open chromatin.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
An enhancer/locus control region is not sufficient to open chromatin.
@ast
An enhancer/locus control region is not sufficient to open chromatin.
@en
type
label
An enhancer/locus control region is not sufficient to open chromatin.
@ast
An enhancer/locus control region is not sufficient to open chromatin.
@en
prefLabel
An enhancer/locus control region is not sufficient to open chromatin.
@ast
An enhancer/locus control region is not sufficient to open chromatin.
@en
P2093
P2860
P356
P1476
An enhancer/locus control region is not sufficient to open chromatin.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.7.3990
P407
P577
1993-07-01T00:00:00Z