CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.
about
Predicting Protein Dynamics and Allostery Using Multi-Protein Atomic Distance Constraints.Exploring Non-obvious Hydrophobic Binding Pockets on Protein Surfaces: Increasing Affinities in Peptide-Protein Interactions.Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors.Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases.Identification of Multiple Druggable Secondary Sites by Fragment Screening against DC-SIGN.Targeted Protein Degradation by Small Molecules.Optimized allosteric inhibition of engineered protein tyrosine phosphatases with an expanded palette of biarsenical small molecules.Exploring the structural origins of cryptic sites on proteins.An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering
P2860
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P2860
CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@ast
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@en
type
label
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@ast
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@en
prefLabel
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@ast
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@en
P2093
P2860
P50
P1476
CryptoSite: Expanding the Drug ...... tion of Cryptic Binding Sites.
@en
P2093
James A Wells
Julie C Mitchell
Leon Bichmann
Omar N Demerdash
Patrick Weinkam
Peter Cimermancic
T Justin Rettenmaier
P2860
P304
P356
10.1016/J.JMB.2016.01.029
P407
P577
2016-02-04T00:00:00Z