Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design.
about
The evolutionary consequences of blood-stage vaccination on the rodent malaria Plasmodium chabaudiHigh antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus modelMicro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in AfricaHumoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malariaContrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparumSafety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial.A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults.Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development.Distinct patterns of diversity, population structure and evolution in the AMA1 genes of sympatric Plasmodium falciparum and Plasmodium vivax populations of Papua New Guinea from an area of similarly high transmissionNon-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay.Strategies for designing and monitoring malaria vaccines targeting diverse antigensWorldwide genetic variability of the Duffy binding protein: insights into Plasmodium vivax vaccine developmentLack of allele-specific efficacy of a bivalent AMA1 malaria vaccineRecent Progress in Functional Genomic Research in Plasmodium falciparumEpidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomalleiLimited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines.Plasmodium immunomics.Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria.Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria.Use of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1.Blood stage vaccines for Plasmodium falciparum: current status and the way forward.Antibodies to polymorphic invasion-inhibitory and non-Inhibitory epitopes of Plasmodium falciparum apical membrane antigen 1 in human malaria.Evidence for erythrocyte-binding antigen 175 as a component of a ligand-blocking blood-stage malaria vaccine.Finding the sweet spots of inhibition: understanding the targets of a functional antibody against Plasmodium vivax Duffy binding proteinEffects of age, hemoglobin type and parasite strain on IgG recognition of Plasmodium falciparum-infected erythrocytes in Malian children.Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1).Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial.Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.Vaccine design via nonnegative lasso-based variable selectionNo recent adaptive selection on the apyrase of Mediterranean Phlebotomus: implications for using salivary peptides to vaccinate against canine leishmaniasis.A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens.Population genetic structure and natural selection of apical membrane antigen-1 in Plasmodium vivax Korean isolatesMolecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implicationsDesigning malaria vaccines to circumvent antigen variabilityOvercoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1.A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in MaliGenetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'.World Malaria Day 2009: what malaria knows about the immune system that immunologists still do not.Bacterially expressed full-length recombinant Plasmodium falciparum RH5 protein binds erythrocytes and elicits potent strain-transcending parasite-neutralizing antibodies.
P2860
Q27318798-98FDDD05-7A57-46A7-B751-A4E003EBC655Q28749979-6749E02D-EF5E-46FC-BC7A-25F401AB5C72Q29464553-CD01036A-1874-4F3B-BAD1-19472B6F58D3Q30942598-ECCE215A-220F-4A9D-B787-4B7B755BE499Q33359552-0D59AACD-2238-49C8-945D-ADF87C74BBC0Q33521214-CF7F30FB-D0E9-4C47-9106-6D546A6D4CC4Q33530106-B56548FD-6687-4332-98B0-7E5DEB21547BQ33598040-009D0167-593D-416F-8DA5-D17AB9684352Q33654911-CF11C3C8-F921-442C-8F41-B191D934ADC2Q33859217-07934BCC-09A7-4453-B00A-31E10DD66EAEQ33939405-3D268124-69A0-4C7E-A37B-1C483056009DQ33959038-7DBCA34D-9245-437C-AFFC-3678DEC0844FQ33988630-9DFAD69C-C17D-4A2D-B3ED-1D8D1540E99CQ34011922-5A91F705-0AAD-445E-9FD8-D6E9167B55B5Q34094261-D74AF2E1-D126-42F7-AD49-0E5BF3F0EB2AQ34105240-C81E817C-4064-4E10-8DEA-952970FDF0F0Q34416904-91445C5A-3FB0-49D0-AC3C-C3F00E2CEAA7Q34419934-1041BF33-8425-4C9A-B5EE-AEE84B731854Q34441098-EA055092-405B-4657-AC35-0EAE6094D55DQ34507190-7AB8C4CE-F9AF-45C7-A64F-3B7E3BA91959Q34596157-DAF34190-F8AD-4D58-A4BF-5AA423E84DABQ34663978-6D011F37-7B66-4612-AAC8-0FCAAD9D644DQ34827195-303D0888-4408-4478-953D-20701622A6A3Q34937705-F68F80D3-C5CA-4950-85EC-09EA47777B6CQ34994491-3107D41B-9D2D-4385-B1F3-7741206B18D5Q35017067-E5C3319D-123A-4BA2-A0EB-9B689AE151AFQ35037036-F3909296-FF89-444F-A7D0-BBEA8D3F059FQ35048336-75FAFA04-3B82-45AE-A336-B282213F2FB4Q35079832-45082C34-27CB-4011-BE79-76A76D94CC9AQ35328896-4B058EC2-30DF-44BB-8231-282893334C5AQ35539678-880E8C51-0C12-4554-8386-9DA5DA4F0EDCQ36141540-98806E9C-FC9F-4423-933F-2528CA877546Q36286806-A69B37A3-D8B2-46A7-BF69-61CC07A245FBQ36509831-AD7B4D84-AE40-4D37-BB5C-F135229A37D2Q36514853-CEEFFB60-2F6A-4221-8BB4-C376B93C91A4Q36826951-3B164E4B-FC60-4A28-B097-83DE0F2ACFB1Q37267850-1CAD48DE-C25C-43C5-ADEA-1B0CA56AB1FEQ37313879-F63E2708-ACD6-41EF-8DA5-E306F59A32FFQ37426820-6F5FF2D8-EA44-4EC1-904B-76A2C74AF609Q37548216-072AEA71-2398-4767-8027-9852F2FFF9D3
P2860
Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Population structure of the ge ...... plications for vaccine design.
@ast
Population structure of the ge ...... plications for vaccine design.
@en
type
label
Population structure of the ge ...... plications for vaccine design.
@ast
Population structure of the ge ...... plications for vaccine design.
@en
prefLabel
Population structure of the ge ...... plications for vaccine design.
@ast
Population structure of the ge ...... plications for vaccine design.
@en
P2093
P2860
P50
P356
P1476
Population structure of the ge ...... plications for vaccine design.
@en
P2093
Amed Ouattara
Deirdre Joy
Jianbing Mu
Junhui Duan
Xin-Zhuan Su
P2860
P304
P356
10.1073/PNAS.0802328105
P407
P50
P577
2008-05-30T00:00:00Z