Biologic therapies in rheumatology: lessons learned, future directions.
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Disease modifying immunosuppressant drugs for juvenile-onset systemic lupus erythematosusTocilizumabTregalizumab - A Monoclonal Antibody to Target Regulatory T CellsCrystal structure of TNFα complexed with a poxvirus MHC-related TNF binding proteinA metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritisRisk of malignancies using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a systematic review and meta-analysis.An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis.Peripheral blood derived gene panels predict response to infliximab in rheumatoid arthritis and Crohn's disease.In vitro potency, pharmacokinetic profiles, and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupusAntibody-based delivery of IL4 to the neovasculature cures mice with arthritis.Janus kinases: an ideal target for the treatment of autoimmune diseases.Role of macrophage CCAAT/enhancer binding protein delta in the pathogenesis of rheumatoid arthritis in collagen-induced arthritic mice.Applying refinement to the use of mice and rats in rheumatoid arthritis research.Overexpression of TLR2 and TLR9 on monocyte subsets of active rheumatoid arthritis patients contributes to enhance responsiveness to TLR agonists.Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases.Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases.Actin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis.Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sjögren's syndrome.Why can't we find a new treatment for SLE?Randomized controlled trial design in rheumatoid arthritis: the past decade.Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats.Antibody engineering to develop new antirheumatic therapies.Clinically validated approaches to the treatment of autoimmune diseases.Treating arthritis by immunomodulation: is there a role for regulatory T cells?Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets.Hepatotoxicity related to antirheumatic drugs.Juvenile idiopathic arthritis: new insights into classification, measures of outcome, and pharmacotherapy.Biologic therapies in non-rheumatic diseases: lessons for rheumatologists?Designing micro- and nano-particles for treating rheumatoid arthritis.IκB kinase regulation of the TPL-2/ERK MAPK pathway.Anti-TNF-α biotherapies: perspectives for evidence-based personalized medicine.Monoclonal antibody treatments for rheumatoid arthritis.An introduction to biosimilar cancer therapeutics: definitions, rationale for development and regulatory requirements.Preparing for a new generation of biologic therapies: understanding the development and potential of biosimilar cancer therapeutics.Room for more IL-6 blockade? Sarilumab for the treatment of rheumatoid arthritis.A key role for Fut1-regulated angiogenesis and ICAM-1 expression in K/BxN arthritis.Intravenous immunoglobulin: a biological corticosteroid-sparing agent in some autoimmune conditions.Immunogenicity of Biologics in Chronic Inflammatory Diseases: A Systematic Review.Mucosa-associated lymphoid tissue lymphoma translocation 1 as a novel therapeutic target for rheumatoid arthritis.NK cell count as predictor of clinical response in patients with rheumatoid arthritis treated with rituximab.
P2860
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P2860
Biologic therapies in rheumatology: lessons learned, future directions.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Biologic therapies in rheumatology: lessons learned, future directions.
@ast
Biologic therapies in rheumatology: lessons learned, future directions.
@en
type
label
Biologic therapies in rheumatology: lessons learned, future directions.
@ast
Biologic therapies in rheumatology: lessons learned, future directions.
@en
prefLabel
Biologic therapies in rheumatology: lessons learned, future directions.
@ast
Biologic therapies in rheumatology: lessons learned, future directions.
@en
P2860
P356
P1476
Biologic therapies in rheumatology: lessons learned, future directions.
@en
P2093
Vibeke Strand
P2860
P2888
P356
10.1038/NRD2196
P577
2007-01-01T00:00:00Z