Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. - Wikidata - wikimedia - TriplyDB

Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells.

Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells.

http://www.wikidata.org/entity/Q36698689

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Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis Pharmacological Targeting of the Hepcidin/Ferroportin Axis Hepcidin: A Promising Therapeutic Target for Iron Disorders: A Systematic Review The Role of the Multiple Hormonal Dysregulation in the Onset of "Anemia of Aging": Focus on Testosterone, IGF-1, and Thyroid Hormones Testosterone Replacement Therapy and Cardiovascular Risk: A Review Hepcidin: regulation of the master iron regulator Mechanisms of divalent metal toxicity in affective disorders Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement.Hepcidin and sports anemia Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point.Gender difference in relationship between serum ferritin and 25-hydroxyvitamin D in Korean adults Physiology of iron metabolism Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone.The effects of short-term and long-term testosterone supplementation on blood viscosity and erythrocyte deformability in healthy adult mice Serum Ferritin Is Inversely Correlated with Testosterone in Boys and Young Male Adolescents: A Cross-Sectional Study in Taiwan Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans.Progesterone receptor membrane component-1 regulates hepcidin biosynthesis Modulation of hepcidin to treat iron deregulation: potential clinical applications.Effects of Testosterone on Erythropoiesis in a Female Mouse Model of Anemia of Inflammation Risks and benefits of late onset hypogonadism treatment: an expert opinion.Out of balance--systemic iron homeostasis in iron-related disorders The liver: conductor of systemic iron balance.Transdermal testosterone replacement therapy in men.The iron cycle in chronic kidney disease (CKD): from genetics and experimental models to CKD patients.Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.Testosterone supplementation improves anemia in aging male mice.The pathophysiology and pharmacology of hepcidin.Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review.Anaemia in chronic obstructive pulmonary disease: an insight into its prevalence and pathophysiology.Hemoglobin during ribavirin-based HCV therapy is closely related to circulating levels of DHEA.Alterations in Hemoglobin and Serum 25-hydroxyvitamin D are Related Before and After Weight Loss Independent of African Admixture.Regulation of the Iron Homeostatic Hormone Hepcidin.Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.Effect of testosterone on hepcidin, ferroportin, ferritin and iron binding capacity in patients with hypogonadotropic hypogonadism and type 2 diabetes.Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.Current understanding of iron homeostasis.Hepcidin: a real-time biomarker of iron need.Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey.Sex differences in iron status and hepcidin expression in rats.Effects of an Acute Exercise Bout on Serum Hepcidin Levels.

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P2860

Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells.

http://www.wikidata.org/entity/Q36698689

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Carlo Serra

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Cindy N Roy

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Elizabeta Nemeth

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Eric Bachman

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Jerzy Blusztajn

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Martina U Muckenthaler

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Michelle Li

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P2860

Hepcidin and iron regulation, 10 years later.

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

Effects of graded doses of testosterone on erythropoiesis in healthy young and older men.

Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis.

Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4.

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

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280-291

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10.1111/ACEL.12052

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2

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12

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Shalender Bhasin

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235520694

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23399021

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