An atlas of genetic correlations across human diseases and traits - Wikidata - wikimedia - TriplyDB

An atlas of genetic correlations across human diseases and traits

An atlas of genetic correlations across human diseases and traits

http://www.wikidata.org/entity/Q36701237

about

Uncovering the Genetic Architectures of Quantitative Traits Polygenic Epidemiology Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.Progress and promise in understanding the genetic basis of common diseases The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium Autism As a Disorder of High Intelligence Genetic variants linked to education predict longevity The landscape of microbial phenotypic traits and associated genes Genetic Moderation of Stress Effects on Corticolimbic Circuitry Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies How Can Genetic Studies Help Us to Understand Links Between Birth Weight and Type 2 Diabetes?Dissecting the genetics of complex traits using summary association statistics Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia The Genetic Landscape of Renal Complications in Type 1 Diabetes.A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases Assessing the genetic architecture of epithelial ovarian cancer histological subtypes.Genetic loci associated with heart rate variability and their effects on cardiac disease risk.Genome-wide analysis identifies 12 loci influencing human reproductive behavior.An Expanded View of Complex Traits: From Polygenic to Omnigenic Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease.New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology.New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data.LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data.Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci Phenome-wide heritability analysis of the UK Biobank Serum calcium and risk of migraine: a Mendelian randomization study Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data.Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.Generating testable hypotheses for schizophrenia and rheumatoid arthritis pathogenesis by integrating epidemiological, genomic, and protein interaction data Cognitive ability and physical health: a Mendelian randomization study.Overlapping Neural Endophenotypes in Addiction and Obesity.

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An atlas of genetic correlations across human diseases and traits

http://www.wikidata.org/entity/Q36701237

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2015年论文

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2015年论文

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2015年论文

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name

An atlas of genetic correlations across human diseases and traits

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An atlas of genetic correlations across human diseases and traits

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An atlas of genetic correlations across human diseases and traits

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An atlas of genetic correlations across human diseases and traits

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An atlas of genetic correlations across human diseases and traits

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An atlas of genetic correlations across human diseases and traits

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Nature Genetics

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An atlas of genetic correlations across human diseases and traits

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Alkes L Price

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Benjamin M Neale

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Brendan Bulik-Sullivan

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Genetic Consortium for Anorexia Nervosa of the Wellcome Trust Case Control Consortium 3

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Hilary K Finucane

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John R B Perry

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Laramie Duncan

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Nick Patterson

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Po-Ru Loh

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Psychiatric Genomics Consortium

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Socioeconomic inequality in the prevalence of autism spectrum disorder: evidence from a U.S. cross-sectional study

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Five years of GWAS discovery

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

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1236-1241

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10.1038/NG.3406

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11

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47

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Verneri Anttila

Mark Joseph Daly

Elise B Robinson

Alexander Gusev

P577

2015-09-28T00:00:00Z

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26414676

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4797329

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