A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesArginine Demethylation of G3BP1 Promotes Stress Granule AssemblyPRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L BromodomainsChemical probes targeting epigenetic proteins: Applications beyond oncology.Small Molecule Inhibitors of Protein Arginine Methyltransferases.Inhibitors of Protein Methyltransferases and Demethylases.The story of protein arginine methylation: characterization, regulation, and function.A chemical probe toolbox for dissecting the cancer epigenome.Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1).Structural basis of arginine asymmetrical dimethylation by PRMT6.Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.Protein arginine methyltransferase 6 controls erythroid gene expression and differentiation of human CD34+ progenitor cells.Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase.Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases.The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism.Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.Discovery of Decamidine as a New and Potent PRMT1 Inhibitor.TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma.GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.Protein arginine methylation: an emerging regulator of the cell cycle.Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization.Protein methyltransferase inhibitors as precision cancer therapeutics: a decade of discovery.
P2860
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P2860
A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@ast
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@en
type
label
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@ast
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@en
prefLabel
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@ast
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@en
P2093
P2860
P50
P1433
P1476
A Potent, Selective, and Cell- ...... n Arginine Methyltransferases.
@en
P2093
Aiping Dong
Brandon A Speed
Carlo Dela Seña
Fengling Li
Guillermo Senisterra
H Ümit Kaniskan
P2860
P304
P356
10.1021/ACSCHEMBIO.5B00839
P577
2015-11-24T00:00:00Z