Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.
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Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potentialMig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formationAnalysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone.Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.Dual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis.MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity.Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.Human keratinocyte growth factor effects in a porcine model of epidermal wound healingTransgenic mouse model of malignant skin melanomaProgressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic miceBeyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology.Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancerRasGRP1 transgenic mice develop cutaneous squamous cell carcinomas in response to skin wounding: potential role of granulocyte colony-stimulating factorAmphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells.Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis.Modeling cutaneous squamous carcinoma development in the mouseCellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis.Transgenic mice and squamous multistage skin carcinogenesis.Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.Molecular mechanisms of mouse skin tumor promotion.Activated Ha-Ras but not TPA induces transcription through binding sites for activating transcription factor 3/Jun and a novel nuclear factor.Expression of cell-cycle regulator CDK2-associating protein 1 (p12CDK2AP1) in transgenic mice induces testicular and ovarian atrophy in vivo.Liver regeneration and hepatocarcinogenesis in transforming growth factor-alpha-targeted mice.Enhanced sensitivity to tumor growth and development in multistage skin carcinogenesis by transforming growth factor-alpha-induced epidermal growth factor receptor activation but not p53 inactivation.Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene.Distinct genetic loci control development of benign and malignant skin tumours in mice.Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species.
P2860
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P2860
Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@ast
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@en
type
label
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@ast
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@en
prefLabel
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@ast
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@en
P2093
P2860
P356
P1476
Transgenic overexpression of t ...... s in mouse skin tumorigenesis.
@en
P2093
P2860
P304
P356
10.1128/MCB.12.10.4643
P407
P577
1992-10-01T00:00:00Z