Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
about
Intracellular targeting with engineered proteinsImproving the DNA specificity and applicability of base editing through protein engineering and protein delivery.Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery.Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.Intracellular delivery of the PTEN protein using cationic lipidoids for cancer therapy.Development of a Dual-Functional Hydrogel Using RGD and Anti-VEGF Aptamer.Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach.Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS.CRISPR Editing Technology in Biological and Biomedical Investigation.Advances in the delivery of RNA therapeutics: from concept to clinical reality.Applications of CRISPR genome editing technology in drug target identification and validation.Therapeutic genome engineering via CRISPR-Cas systems.CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects.Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.Non-viral delivery of genome-editing nucleases for gene therapy.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Nanoparticles for the delivery of therapeutic antibodies: Dogma or promising strategy?Delivery technologies for genome editing.Intracellular delivery of proteins by nanocarriers.Use of CRISPR/Cas9 to model brain diseases.Therapeutic gene editing: delivery and regulatory perspectivesThe CRISPR/Cas9 system: Their delivery, in vivo and ex vivo applications and clinical development by startups.Protein based therapeutic delivery agents: Contemporary developments and challenges.Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications.Expression of Flp Protein in a Baculovirus/Insect Cell System for Biotechnological Applications.In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.Immunity to CRISPR Cas9 and Cas12a therapeutics.Genome Editing for Cancer Therapy: Delivery of Cas9 Protein/sgRNA Plasmid via a Gold Nanocluster/Lipid Core-Shell Nanocarrier.Engineering the Delivery System for CRISPR-Based Genome Editing.Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.Transduction Methods for Cytosolic Delivery of Proteins and Bioconjugates into Living Cells.CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia.Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide.Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy.The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders.Peptide/Cas9 nanostructures for ribonucleoprotein cell membrane transport and gene edition.Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell Type Specific Gene Editing.Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.Integration of Nanobots Into Neural Circuits As a Future Therapy for Treating Neurodegenerative Disorders.Recent developments in intracellular protein delivery.
P2860
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P2860
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@ast
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@en
type
label
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@ast
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@en
prefLabel
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@ast
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
@en
P2093
P2860
P50
P356
P1476
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
@en
P2093
David R Liu
Dimitra Pouli
Fantao Meng
Holly Rees
John A Zuris
Qiaobing Xu
P2860
P304
P356
10.1073/PNAS.1520244113
P407
P577
2016-02-29T00:00:00Z