A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells.
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Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative AnalysisEpigenetic perturbations in aging stem cellsGenetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionWhen stem cells grow old: phenotypes and mechanisms of stem cell agingEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsGenetic regulation of thymocyte progenitor agingImmunosenescence and organ transplantationSirtuins in hematological aging and malignancyAge-dependent dysregulation of innate immunityStem cell heterogeneity: implications for aging and regenerative medicineSelf-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansionReduced expression of MYC increases longevity and enhances healthspan.Rheumatoid arthritis: a role for immunosenescence?Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow MicroenvironmentThe many faces of hematopoietic stem cell heterogeneityTif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cellsImpact of genomic damage and ageing on stem cell functionAccumulation of DNA damage in the aged hematopoietic stem cell compartmentDistinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.Cell therapy, a new standard in management of chronic critical limb ischemia and foot ulcer.Cdc42 and aging of hematopoietic stem cells.Kidney transplantation in the elderly.Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansionEpigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML.Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycleSome hematopoietic stem cells are more equal than others.Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitorsCells derived from young bone marrow alleviate renal aging.Functional diversity of stem and progenitor cells with B-lymphopoietic potentialAccumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activityProgeroid syndromes: models for stem cell aging?Stem cells and aging: a chicken-or-the-egg issue?A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampusPredicting clonal self-renewal and extinction of hematopoietic stem cells.Lifespan differences in hematopoietic stem cells are due to imperfect repair and unstable mean-reversionManifestations and mechanisms of stem cell aging.Impact of donor age on outcome after allogeneic hematopoietic cell transplantation.Chronic exposure to a TLR ligand injures hematopoietic stem cells.
P2860
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P2860
A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A new mechanism for the aging ...... but not individual stem cells.
@ast
A new mechanism for the aging ...... but not individual stem cells.
@en
type
label
A new mechanism for the aging ...... but not individual stem cells.
@ast
A new mechanism for the aging ...... but not individual stem cells.
@en
prefLabel
A new mechanism for the aging ...... but not individual stem cells.
@ast
A new mechanism for the aging ...... but not individual stem cells.
@en
P2093
P2860
P1433
P1476
A new mechanism for the aging ...... but not individual stem cells.
@en
P2093
Christa E Muller-Sieburg
Hans B Sieburg
Rebecca H Cho
P2860
P304
P356
10.1182/BLOOD-2007-11-123547
P407
P577
2008-04-15T00:00:00Z