Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study
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P1343
Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingUnderstanding FRET as a research tool for cellular studiesThe shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapyIL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cellsDistinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cellsSeeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cellsComparative model building of interleukin-7 using interleukin-4 as a template: a structural hypothesis that displays atypical surface chemistry in helix D important for receptor activation.Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein.The role of endogenous interleukin-2 in proliferation of human carcinoma cell linesProtein-protein interaction as a predictor of subcellular locationInsulin receptor activation with transmembrane domain ligands.The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cellsA new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.Pharmaceutical intervention in the JAK/STAT signaling pathway.Dynamic, yet structured: The cell membrane three decades after the Singer-Nicolson modelCentral role for interleukin-2 in type 1 diabetes.Distinct spatial relationship of the interleukin-9 receptor with interleukin-2 receptor and major histocompatibility complex glycoproteins in human T lymphoma cells.Cholesterol-dependent clustering of IL-2Ralpha and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts.Mechanistic diversity of cytokine receptor signaling across cell membranes.Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes.Anergy induction by dimeric TCR ligandsInterleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imagingMHC I Expression Regulates Co-clustering and Mobility of Interleukin-2 and -15 Receptors in T CellsVisualization of protein interactions in living cells.Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain.The common γ-chain cytokine receptor: tricks-and-treats for T cells.PIN-G--a novel reporter for imaging and defining the effects of trafficking signals in membrane proteins.Signaling T-cell survival and death by IL-2 and IL-15.Raft and cytoskeleton associations of an ABC transporter: P-glycoprotein.Visualization of Protein Interactions in Living Cells.Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments.Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes.Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the gamma chain.GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines.IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells.Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling.Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor.
P2860
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P2860
Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@ast
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@en
type
label
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@ast
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@en
prefLabel
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@ast
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@en
P2093
P2860
P356
P1476
Preassembly of interleukin 2 ( ...... esonance energy transfer study
@en
P2093
A Alileche
C K Goldman
S Damjanovich
T A Waldmann
P2860
P304
13134-13139
P356
10.1073/PNAS.94.24.13134
P407
P4510
P577
1997-11-01T00:00:00Z