Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes - Wikidata - wikimedia - TriplyDB

Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes

Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes

http://www.wikidata.org/entity/Q36720530

about

Repurposing metformin: an old drug with new tricks in its binding pockets Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR Crosstalk between Autophagy and Apoptosis: Potential and Emerging Therapeutic Targets for Cardiac Diseases Erythropoietin and diabetes mellitus New mechanisms of metformin action: Focusing on mitochondria and the gut FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus Myocardial autophagic energy stress responses--macroautophagy, mitophagy, and glycophagy Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy Autophagy: an adaptive physiological countermeasure to cellular senescence and ischaemia/reperfusion-associated cardiac arrhythmias New Insights for Oxidative Stress and Diabetes Mellitus Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein.Effects of 1,25-dihydroxyvitamin D3 on pathological changes in rats with diabetic cardiomyopathy.Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy.Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice.PRKAA1/AMPKα1 is required for autophagy-dependent mitochondrial clearance during erythrocyte maturation Autophagy and oxidative stress in cardiovascular diseases.Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy.Association between Diabetes and Risk of Aortic Dissection: A Case-Control Study in a Chinese Population.Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats.Blocking Nuclear Factor-Kappa B Protects against Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice High Glucose Induces Down-Regulated GRIM-19 Expression to Activate STAT3 Signaling and Promote Cell Proliferation in Cell Culture Regeneration in the nervous system with erythropoietin AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1.Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome Activation with Mitophagy.Metformin Promotes Apoptosis but Suppresses Autophagy in Glucose-Deprived H4IIE Hepatocellular Carcinoma Cells.Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy Molecular regulation of autophagy and its implications for metabolic diseases.Autophagy regulation by nutrient signaling.Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids.FoxO1 controls lysosomal acid lipase in adipocytes: implication of lipophagy during nutrient restriction and metformin treatment.Cardiomyocyte health: adapting to metabolic changes through autophagy.Mammalian target of rapamycin signaling in cardiac physiology and disease.New insight for metformin against bladder cancer.The importance of autophagy in cardioprotection.Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes.

P2860

Q22250976-97B4423C-CBD5-4B21-B6BA-8873067A7B0B Q26749047-7814802B-B4CD-4882-8BD5-8F35C9CFFBA3 Q26767369-3D9C208F-3F71-4131-A437-837743E5E594 Q26777878-68FC39A3-FFE9-4B2E-B4E4-A17A93947686 Q26778766-01FA0339-B3BE-4B14-8981-870F4EEAC96E Q26800615-818E3CBB-ABE2-4CAF-A813-EEA63EA9FA09 Q26995370-CE4535DA-8CCA-4A78-9EA3-1EF3253D0D9E Q27001165-9F3B08B8-E0E3-4D0F-B882-759A9F2F76FE Q28070047-6E113139-ED01-4BB8-9ADE-D618EC34ADB7 Q28080679-2CAC0492-9EF5-4E79-BA6E-CBFD124F9F78 Q28533775-0A057F3A-5DED-47A0-A34D-16662BD87648 Q33553613-8C75E8B3-B506-463E-8567-5DC823809337 Q33781356-4876A0C1-276E-4DEA-BD3B-5AFF89A39CA9 Q33842696-F24DD8D7-95F1-46B3-84DA-307D321112AE Q34311221-1EFD084A-6FC6-4CB4-BB09-951EC51709D3 Q34388770-FCFE3337-7A13-4E02-BE7E-2DBB7876E840 Q34506174-B794B56B-A7CD-4B29-9F80-1CD7C89A341D Q35034843-D3244D30-9812-4507-B9DE-A79DE228D500 Q35148462-170A536B-0E47-4401-A37C-6F46A90B3EEB Q35667361-986F8A5E-0ADE-49FE-9D9F-309DBE5D399C Q35671780-BB14A498-9F74-45D0-A8C1-AC37A4EB0D23 Q35840030-C17F7043-1FB3-4EBF-9D8D-DD11323302EC Q35936441-EF686CFA-54FB-4099-AA7A-C321CF845757 Q35941341-D7E460D8-3CE2-491A-B26B-17EA666392D4 Q35996269-CCBABFF4-2335-4909-BF3B-17AF13211592 Q36247651-911E5EF7-4401-45F8-86F3-C398700237A4 Q36311546-FAA6B84B-4EFA-409A-A741-A01970236B79 Q36386652-B6BF631E-7CF5-40F5-A4F1-CF49570DFC62 Q36418806-72E856AA-6C32-44C4-BA3A-B0A631EEA06E Q36632912-7680B254-8804-4641-A676-A98643294767 Q36846777-90310197-CF8C-4745-BAFC-8BC710F0A1A8 Q36874400-C92A7252-C477-40B9-B81F-3DFFB8BA9C67 Q37429067-DC3B182F-F3B5-4DEE-AD91-C90E613B3781 Q37575390-0CCF160F-406C-4C73-BCA0-F5C9A4ACAF63 Q37577484-A8A86034-297B-452A-B61C-48A884D195AC Q37632778-24A96367-6043-40EC-923B-E8FD9F4F4128 Q37715817-B716B21F-743F-4374-81AB-B08D6AA0923A Q37733377-BBE64992-63A9-4A15-8533-576E184BFE89 Q38162827-CC2BE6B4-0BC6-4D04-90E8-8F762A418FDD Q38336391-E7B73BA8-E7EA-4B2C-B925-0237975498E4

P2860

Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes

http://www.wikidata.org/entity/Q36720530

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@ast

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@en

type

label

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@ast

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@en

prefLabel

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@ast

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@en

P1433

Q36720530-CC1A7A59-A7D6-4120-B8BE-A1D2D247FB3A

P1476

Q36720530-2E7790E5-9D61-4251-89B7-1BFEA1667A6F

P2093

Q36720530-5D5AAF4A-9CA0-426B-ACBF-3B475F547536

Q36720530-62BF392A-28CF-4462-B601-21B0554121CE

Q36720530-6B3EA0DB-0BAC-4F63-BEAB-557382609A15

Q36720530-BEB75A94-5250-4D18-AC14-E0992FF26547

Q36720530-D81A8D84-A3D8-422A-A8F0-C182BC03ED4F

P2860

Q36720530-0A2F916C-5D5B-41E5-B43A-D0F42730BF5D

Q36720530-0C11B2AF-CBE6-4156-9DC2-38ECDD2F45E6

Q36720530-13B58EEF-21AD-468C-9686-493333627EE5

Q36720530-1796870A-3178-4D96-AB29-CF7B8DF42A6C

Q36720530-1BB4AAA6-3F26-43FA-A43B-437ABB9E667C

Q36720530-29F243CD-CDB2-410A-B662-5B395B0AA620

Q36720530-34AA872E-FEE0-4E99-B3BE-4C7E8BDB13C7

Q36720530-39483CC6-46F1-43C7-ADF9-6A5906C162AE

Q36720530-3B3C24F6-D13F-4A24-AB47-EF398BE9F648

Q36720530-3E137EEC-C810-408D-9E48-927DD97562DC

P304

Q36720530-700277A5-9654-485B-A365-29AF43A162B8

P31

Q36720530-6329EA4E-AB25-4710-912A-AAE2403E5C97

P356

Q36720530-3259F61C-7CCF-40A2-8DAD-97302F548D8D

P407

Q36720530-75FEDF5D-12B4-45CD-A7BF-7CB8928F386B

P433

Q36720530-EA908A92-C4AB-4142-B72B-F6129C6504A7

P478

Q36720530-677FD379-79B9-4F3C-9DC4-3B96342BA995

P577

Q36720530-A9A9B6B3-E0E2-4696-B4DE-799247CB4091

P5875

Q36720530-64B1F9ED-C41E-498A-8F3C-329681359F57

P698

Q36720530-0D46EF04-9D03-4C71-BBD4-A1FAA824C024

P921

Q36720530-F7704492-ED7A-4F8F-A966-788151263FC1

P932

Q36720530-AEA08941-EF6A-405D-A2E3-5EE07E258E7B

P356

P1433

P1476

Dissociation of Bcl-2-Beclin1 ...... omyocyte apoptosis in diabetes

@en

P2093

Chaoyong He

http://www.w3.org/2001/XMLSchema#string

Hongliang Li

http://www.w3.org/2001/XMLSchema#string

Huaiping Zhu

http://www.w3.org/2001/XMLSchema#string

Ming-Hui Zou

http://www.w3.org/2001/XMLSchema#string

Zhonglin Xie

http://www.w3.org/2001/XMLSchema#string

P2860

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

Inhibition of macroautophagy triggers apoptosis

Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

Methods in mammalian autophagy research

The role of autophagy during the early neonatal starvation period

P304

1270-1281

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DB12-0533

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

62

http://www.w3.org/2001/XMLSchema#string

P577

2012-12-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

233881131

http://www.w3.org/2001/XMLSchema#string

P698

23223177

http://www.w3.org/2001/XMLSchema#string

P921

P932

3609561

http://www.w3.org/2001/XMLSchema#string