Reduction of the rate of protein translation in patients with myotonic dystrophy 2
about
ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2Arginine methylation of the cellular nucleic acid binding protein does not affect its subcellular localization but impedes RNA bindingRAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disordersDefining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteinsYeast Gis2 and its human ortholog CNBP are novel components of stress-induced RNP granules.Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes.The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation.Myotonic dystrophies 1 and 2: complex diseases with complex mechanisms.Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patternsBridging integrator 1 (BIN1) protein expression increases in the Alzheimer's disease brain and correlates with neurofibrillary tangle pathologyDifferences in aberrant expression and splicing of sarcomeric proteins in the myotonic dystrophies DM1 and DM2.Mutant (CCTG)n expansion causes abnormal expression of zinc finger protein 9 (ZNF9) in myotonic dystrophy type 2.Beyond the binding site: in vivo identification of tbx2, smarca5 and wnt5b as molecular targets of CNBP during embryonic development.Enhanced translation of mRNAs encoding proteins involved in mRNA translation during recovery from heat shock.High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.Small molecules that target the toxic RNA in myotonic dystrophy type 2.Overexpression of CUGBP1 in skeletal muscle from adult classic myotonic dystrophy type 1 but not from myotonic dystrophy type 2.RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2RNA-binding protein misregulation in microsatellite expansion disordersAn Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies.Thermal injury activates the eEF2K-dependent eEF2 pathway in pediatric patients.Molecular mechanisms of muscle atrophy in myotonic dystrophies.Altered expression and splicing of Ca(2+) metabolism genes in myotonic dystrophies DM1 and DM2.CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMycCharacterization and regulation of mechanical loading-induced compensatory muscle hypertrophy.Clinical aspects, molecular pathomechanisms and management of myotonic dystrophies.Deciphering the cellular and molecular roles of cellular nucleic acid binding protein during cranial neural crest development.Stress puts TIA on TOP.Myotonic Dystrophy Type 2: An Update on Clinical Aspects, Genetic and Pathomolecular Mechanism.Myotonic dystrophy type 2 and modifier genes: an update on clinical and pathomolecular aspects.Biomolecular diagnosis of myotonic dystrophy type 2: a challenging approach.Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy.
P2860
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P2860
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@ast
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@en
type
label
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@ast
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@en
prefLabel
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@ast
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@en
P2093
P2860
P1476
Reduction of the rate of protein translation in patients with myotonic dystrophy 2
@en
P2093
Bingwen Jin
Claudia Huichalaf
Lubov Timchenko
Partha Sarkar
P2860
P304
P356
10.1523/JNEUROSCI.1983-09.2009
P407
P577
2009-07-01T00:00:00Z