about
Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han populationCloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig.Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review.The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression.Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period.Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif.The role of pharmacogenetically-variable cytochrome P450 enzymes in drug abuse and dependence.Phenobarbital induction of cytochrome P-450 gene expression.The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role.Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription.A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor.Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 geneP450 and human cancer.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat.trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines.Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells.The molecular mechanism regulating 24-hour rhythm of CYP2E1 expression in the mouse liver.A novel lipopolysaccharide-modulated Jun binding repressor in intron 2 of CYP2E1.Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family.Zonation of hepatic cytochrome P-450 expression and regulation.Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility.Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake.Role of beta-catenin in the adult liver.Expression of cytochrome P450 enzymes in hepatic organoid reconstructed by rat small hepatocytes.Analysis of the promoter of the cytochrome P-450 2B2 gene in the rat.Identification and characterization of a novel tissue-specific transcriptional activating element in the 5'-flanking region of the CYP2A3 gene predominantly expressed in rat olfactory mucosa.Expression of CYP2E1 in human lung and kidney during development and in full-term placenta: a differential methylation of the gene is involved in the regulation process.
P2860
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P2860
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Transcriptional control of the rat hepatic CYP2E1 gene
@ast
Transcriptional control of the rat hepatic CYP2E1 gene
@en
type
label
Transcriptional control of the rat hepatic CYP2E1 gene
@ast
Transcriptional control of the rat hepatic CYP2E1 gene
@en
prefLabel
Transcriptional control of the rat hepatic CYP2E1 gene
@ast
Transcriptional control of the rat hepatic CYP2E1 gene
@en
P2860
P356
P1476
Transcriptional control of the rat hepatic CYP2E1 gene
@en
P2093
P2860
P304
P356
10.1128/MCB.10.9.4495
P407
P577
1990-09-01T00:00:00Z