Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae.
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Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase familyDual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processingEndoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavageIsolation and DNA sequence of the STE14 gene encoding farnesyl cysteine: carboxyl methyltransferase.The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane.Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone.Mating pheromones of the fission yeast Schizosaccharomyces pombe: purification and structural characterization of M-factor and isolation and analysis of two genes encoding the pheromoneA novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursorSynthesis and application of fluorescent ras proteins for live-cell imaging.Isoprenylcysteine methylation and demethylation regulate abscisic acid signaling in Arabidopsis.Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterizationPrelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase: development of novel inhibitors.Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activityNon-Substrate Based, Small Molecule Inhibitors of the Human Isoprenylcysteine Carboxyl Methyltransferase.Biogenesis of the Saccharomyces cerevisiae pheromone a-factor, from yeast mating to human disease.Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor.Genes encoding farnesyl cysteine carboxyl methyltransferase in Schizosaccharomyces pombe and Xenopus laevis.Fungal lipopeptide mating pheromones: a model system for the study of protein prenylationLipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions.HIV-protease inhibitors block the enzymatic activity of purified Ste24p.Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear laminaEndoproteolytic processing of a farnesylated peptide in vitro.Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activityThe biochemistry of ras p21.A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.Prenylcysteine alpha-carboxyl methyltransferase expression and function in Arabidopsis thaliana.Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents.H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway.Functional oligomerization of the Saccharomyces cerevisiae isoprenylcysteine carboxyl methyltransferase, Ste14p.Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).A novel post-translational modification of yeast elongation factor 1A. Methylesterification at the C terminus.Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors.Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p.a-Factor: a chemical biology tool for the study of protein prenylation.Epimerization-free access to C-terminal cysteine peptide acids, carboxamides, secondary amides, and esters via complimentary strategies.
P2860
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P2860
Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@ast
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@en
type
label
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@ast
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@en
prefLabel
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@ast
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@en
P2860
P356
P1476
Farnesyl cysteine C-terminal m ...... t in Saccharomyces cerevisiae.
@en
P2093
P2860
P304
P356
10.1128/MCB.10.10.5071
P407
P577
1990-10-01T00:00:00Z