The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.
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Cryptococcal meningitis: A neglected NTD?The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity.Recent advances in AIDS-related cryptococcal meningitis treatment with an emphasis on resource limited settings.Activity of VT-1129 against Cryptococcus neoformans clinical isolates with high fluconazole MICs.The antifungal pipeline: a reality check.Drugs in Clinical Development for Fungal Infections.Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds.Antifungal resistance: current trends and future strategies to combat.Cryptococcosis today: It is not all about HIV infection.VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans.Dermatophyte Resistance to Antifungal Drugs: Mechanisms and Prospectus.
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P2860
The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@ast
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@en
type
label
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@ast
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@en
prefLabel
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@ast
The Investigational Fungal Cyp ...... rmans and Cryptococcus gattii.
@en
P2093
P2860
P356
P1476
The Investigational Fungal Cyp ...... ormans and Cryptococcus gattii
@en
P2093
Annette W Fothergill
Carol B Bolden
Edward P Garvey
Elizabeth Ottinger
Naureen Iqbal
Nina T Grossman
Robert J Schotzinger
Stephen R Brand
Thomas F Patterson
William J Hoekstra
P2860
P304
P356
10.1128/AAC.02770-15
P407
P577
2016-03-25T00:00:00Z