Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing - Wikidata - wikimedia - TriplyDB

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

http://www.wikidata.org/entity/Q36730697

about

A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.Granzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.Hypofractionated stereotactic radiation therapy activates the peripheral immune response in operable stage I non-small-cell lung cancer.Mechanical Criterion for the Rupture of a Cell Membrane under Compression.Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse.Distinct patterns of cytolytic T-cell activation by different tumour cells revealed by Ca2+ signalling and granule mobilization.Mechanical Communication at the Immunological Synapse.Cytoskeletal control of B cell responses to antigens.Mechanosensing drives acuity of αβ T-cell recognition.Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity.Dynamic microtubules regulate cellular contractility during T-cell activation.Biophysical isolation and identification of circulating tumor cells.Receptor-mediated cell mechanosensing.Epithelial-Mesenchymal Transition in Pancreatic Cancer: A Review.Micropipette force probe to quantify single-cell force generation: application to T-cell activation.Probing Synaptic Biomechanics Using Micropillar Arrays.Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse.Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells.Actin retrograde flow controls natural killer cell response by regulating the conformation state of SHP-1.Feeling Stress: The Mechanics of Cancer Progression and Aggression.Mechanical forces in the immune system.Frontiers of Complex Disease Mechanisms: Membrane Surface Tension May Link Genotype to Phenotype in Glaucoma.Signals Controlling Lytic Granule Polarization at the Cytotoxic Immune Synapse.Mechanosensing in the immune response.LFA-1 in T Cell Migration and Differentiation.The Non-Hemostatic Aspects of Transfused Platelets.αβ T Cell Receptor Mechanosensing Forces out Serial Engagement The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes

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P2860

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

http://www.wikidata.org/entity/Q36730697

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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type

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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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prefLabel

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

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J.CELL.2016.01.021

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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

@en

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Alon Oyler-Yaniv

http://www.w3.org/2001/XMLSchema#string

Audrey Le Floc'h

http://www.w3.org/2001/XMLSchema#string

Benjamin M Whitlock

http://www.w3.org/2001/XMLSchema#string

Gregory Giannone

http://www.w3.org/2001/XMLSchema#string

Judy Lieberman

http://www.w3.org/2001/XMLSchema#string

Lance C Kam

http://www.w3.org/2001/XMLSchema#string

Morgan Huse

http://www.w3.org/2001/XMLSchema#string

Nicolas Biais

http://www.w3.org/2001/XMLSchema#string

Roshni Basu

http://www.w3.org/2001/XMLSchema#string

Weiyang Jin

http://www.w3.org/2001/XMLSchema#string

P2860

A single class II myosin modulates T cell motility and stopping, but not synapse formation

Cell movement is guided by the rigidity of the substrate.

Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.

Use the force: membrane tension as an organizer of cell shape and motility

Controversy and consensus regarding myosin II function at the immunological synapse

Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse

Force generation upon T cell receptor engagement

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100-110

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scholarly article

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10.1016/J.CELL.2016.01.021

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1

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165

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Farokh Dotiwala

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2016-02-25T00:00:00Z

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26924577

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4808403

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