CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli
about
Molecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphataseIdentification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45Lineage- and differentiation stage-specific expression of LSM-1 (LPAP), a possible substrate for CD45, in human hematopoietic cellsDifferential requirements of CD45 for lymphocyte development and functionCD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturationThe unique amino-terminal domain of p56lck regulates interactions with tyrosine protein phosphatases in T lymphocytesActivated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells.CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influxT cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival.T-cell tolerance and autoimmune diabetes.Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells.Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor.The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillationsLeukocyte common antigen (CD45) is required for immunoglobulin E-mediated degranulation of mast cells.Mutational analysis of Lck in CD45-negative T cells: dominant role of tyrosine 394 phosphorylation in kinase activity.Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases.Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulationSignal transduction, mitotic catastrophes, and death in T-cell development.Transmembrane signalling in eukaryotes: a comparison between higher and lower eukaryotes.The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection.CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.Adhesive interactions in thymic development: does selective expression of CD45 isoforms promote stage-specific microclustering in the assembly of functional adhesive complexes on differentiating T lineage lymphocytes?Antigen receptor-initiated growth inhibition is blocked in CD45-loss variants of a mature B lymphoma, with limited effects on apoptosis.CTLA-4, a negative regulator of T-lymphocyte activation.Regulation of cell signaling by the protein tyrosine phosphatases, CD45 and SHP-1.Coordinate change in phenotype in a mouse cell line selected for CD8 expression.CD3 antigen-mediated calcium signals and protein kinase C activation are higher in CD45R0+ than in CD45RA+ human T lymphocyte subsets.Reconstitution of interactions between protein-tyrosine phosphatase CD45 and tyrosine-protein kinase p56(lck) in nonlymphoid cells.The role of intron sequences in high level expression from CD45 cDNA constructs.Non-responsiveness of antigen-experienced CD4 T cells reflects more stringent co-stimulatory requirements.Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytesAntiproliferative action of interferon-α requires components of T-cell-receptor signalling
P2860
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P2860
CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@ast
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@en
type
label
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@ast
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@en
prefLabel
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@ast
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@en
P2093
P2860
P356
P1476
CD8+ T-cell clones deficient i ...... ses to T-cell receptor stimuli
@en
P2093
C T Weaver
J O Nelson
J T Pingel
M L Thomas
P2860
P304
P356
10.1128/MCB.11.9.4415
P407
P577
1991-09-01T00:00:00Z