pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation. - Wikidata - wikimedia - TriplyDB

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

http://www.wikidata.org/entity/Q36731316

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HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia The VHL tumor suppressor: master regulator of HIF Sequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspective Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts Cilium assembly and disassembly The Role of PTEN in Tumor Angiogenesis Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma.MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.VHL and PTEN loss coordinate to promote mouse liver vascular lesions.Germline PTEN mutation Cowden syndrome: an underappreciated form of hereditary kidney cancer.Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability.β-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma.A versatile modular vector system for rapid combinatorial mammalian genetics Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury.Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization Renal cancer: oxygen meets metabolism Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells.Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms.Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model.Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst Formation WSB1 promotes tumor metastasis by inducing pVHL degradation Mitotic spindle (DIS)orientation and DISease: cause or consequence?PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.Candidate tumor suppressor and pVHL partner Jade-1 binds and inhibits AKT in renal cell carcinoma Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin.Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster.Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis.The perennial organelle: assembly and disassembly of the primary cilium.Constructing and deconstructing roles for the primary cilium in tissue architecture and cancer.Regulating the transition from centriole to basal body Nervous system involvement in von Hippel-Lindau disease: pathology and mechanisms.The role of HIF1α in renal cell carcinoma tumorigenesis.The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease.HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond.Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.

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P2860

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

http://www.wikidata.org/entity/Q36731316

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

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2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@ast

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@en

type

label

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@ast

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@en

prefLabel

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@ast

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@en

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P1433

The EMBO Journal

P1476

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.

@en

P2093

Andrea Minola

http://www.w3.org/2001/XMLSchema#string

Claudio R Thoma

http://www.w3.org/2001/XMLSchema#string

Holger Moch

http://www.w3.org/2001/XMLSchema#string

Manuela Hitz

http://www.w3.org/2001/XMLSchema#string

Matteo Montani

http://www.w3.org/2001/XMLSchema#string

Strahil Georgiev

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Wilhelm Krek

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P2860

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

von Hippel-Lindau disease

A novel quasi-viral agent, MaTu, is a two-component system

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

Animal models of fetal renal disease.

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3.

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

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1747-1757

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10.1038/EMBOJ.2008.96

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12

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27

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5351909

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18497742

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2435131

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