A small-molecule E2F inhibitor blocks growth in a melanoma culture model. - Wikidata - wikimedia - TriplyDB

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

http://www.wikidata.org/entity/Q36737122

about

RB1: a prototype tumor suppressor and an enigma E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish Arf induction by Tgfβ is influenced by Sp1 and C/ebpβ in opposing directions Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.E2F inhibition synergizes with paclitaxel in lung cancer cell lines A complex task? Direct modulation of transcription factors with small molecules.Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.Classic "broken cell" techniques and newer live cell methods for cell cycle assessment Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer.A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts.Therapeutical potential of deregulated lysine methyltransferase SMYD3 as a safe target for novel anticancer agents.The stress of coping with E2F loss Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel.E2F1-mediated human POMC expression in ectopic Cushing's syndrome.E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis.EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis.E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.E2F1 inhibition mediates cell death of metastatic melanoma.Cell Cycle Regulators and Lineage-Specific Therapeutic Targets for Cushing Disease

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P2860

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

http://www.wikidata.org/entity/Q36737122

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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type

label

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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prefLabel

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

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0008-5472.CAN-08-0121

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Cancer Research

P1476

A small-molecule E2F inhibitor blocks growth in a melanoma culture model.

@en

P2093

Courtney A Kurtyka

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Harshani Lawrence

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Sandhya Boyapalle

http://www.w3.org/2001/XMLSchema#string

Shen-Shu Sung

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W Douglas Cress

http://www.w3.org/2001/XMLSchema#string

Wayne Guida

http://www.w3.org/2001/XMLSchema#string

Yihong Ma

http://www.w3.org/2001/XMLSchema#string

P2860

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

E2F activity is regulated by cell cycle-dependent changes in subcellular localization

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

Sibling rivalry in the E2F family

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity.

Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.

P304

6292-6299

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scholarly article

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10.1158/0008-5472.CAN-08-0121

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15

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68

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2008-08-01T00:00:00Z

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18676853

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3615411

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