Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
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Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationEpigenetic Regulation of Chondrocyte Catabolism and Anabolism in OsteoarthritisOsteoarthritis in the XXIst century: risk factors and behaviours that influence disease onset and progressionSignificance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective.Mitochondrial epigenetics in bone remodeling during hyperhomocysteinemiaAssociation of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylationEpigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders.Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes.Characterization of the cartilage DNA methylome in knee and hip osteoarthritisSelective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions.Epigenetics and Osteoarthritis.Emerging targets in osteoarthritis therapy.Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis.Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic riskIdentification of differentially methylated regions in new genes associated with knee osteoarthritis.Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.Epigenetic and microRNA regulation during osteoarthritis developmentPromoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC).MicroRNA-363 and GATA-1 are regulated by HIF-1α in K562 cells under hypoxia.Sirtuins in neurodegenerative diseases: an update on potential mechanisms.DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts.Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses.Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, α-Ketoglutarate (α-KG), and DNA hydroxymethylation levels by interleukin-1β in primary human chondrocytes.Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes.Osteoarthritis year in review 2013: biology.Epigenetic mechanisms and non-coding RNAs in osteoarthritis.Epigenetics of osteoarticular diseases: recent developments.Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.DNA Methylation Profiling in Chondrocyte Dedifferentiation In Vitro.Epigenetic differences in human cartilage between mild and severe OA.The Disease-Modifying Effects of Hyaluronan in the Osteoarthritic Disease StateDNA Methylation in Osteoarthritis.The Epigenomic Landscape in Osteoarthritis.ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.Stable 5-Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation.The first international workshop on the epigenetics of osteoarthritis.Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage-bone crosstalk.Genomics and epigenomics in rheumatic diseases: what do they provide in terms of diagnosis and disease management?Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes.
P2860
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P2860
Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Regulated transcription of hum ...... c proximal promoter CpG sites.
@ast
Regulated transcription of hum ...... c proximal promoter CpG sites.
@en
type
label
Regulated transcription of hum ...... c proximal promoter CpG sites.
@ast
Regulated transcription of hum ...... c proximal promoter CpG sites.
@en
prefLabel
Regulated transcription of hum ...... c proximal promoter CpG sites.
@ast
Regulated transcription of hum ...... c proximal promoter CpG sites.
@en
P2093
P2860
P356
P1476
Regulated transcription of hum ...... c proximal promoter CpG sites.
@en
P2093
Helmtrud I Roach
Jonathan M Coico
Kei Imagawa
Kenneth B Marcu
Ko Hashimoto
Mary B Goldring
María C de Andrés
Miguel Otero
P2860
P304
10061-10072
P356
10.1074/JBC.M112.421156
P407
P577
2013-02-15T00:00:00Z