Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination. - Wikidata - wikimedia - TriplyDB

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.

http://www.wikidata.org/entity/Q36745578

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The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention Pharmacology and Clinical Drug Candidates in Redox Medicine Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection PALB2: the hub of a network of tumor suppressors involved in DNA damage responses HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction Comparative analysis of NRF2-responsive gene expression in AcPC-1 pancreatic cancer cell line Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety Target competition: transcription factors enter the limelight Dietary regulation of Keap1/Nrf2/ARE pathway: focus on plant-derived compounds and trace minerals.SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.Engineering a genetically encoded competitive inhibitor of the KEAP1-NRF2 interaction via structure-based design and phage display.Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.Role of Nrf2 and Autophagy in Acute Lung Injury The emerging role of the Nrf2-Keap1 signaling pathway in cancer Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination Monitoring Keap1-Nrf2 interactions in single live cells.Molecular and chemical regulation of the Keap1-Nrf2 signaling pathway.Conservation of the Keap1-Nrf2 System: An Evolutionary Journey through Stressful Space and Time.Diabetic cardiomyopathy: role of the E3 ubiquitin ligase.Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.Human dipeptidyl peptidase III mRNA variant I and II are expressed concurrently in multiple tumor derived cell lines and translated at comparable efficiency in vitro.KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination.AAV-Nrf2 Promotes Protection and Recovery in Animal Models of Oxidative Stress.Transcriptional Regulation by Nrf2.The Role of Nrf2 in Cardiovascular Function and Disease.CDK20 interacts with KEAP1 to activate NRF2 and promotes radiochemoresistance in lung cancer cells.Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain.Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides thetaiotaomicron.Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities.A novel plant enzyme with dual activity: an atypical Nudix hydrolase and a dipeptidyl peptidase III.Dipeptidyl peptidase 3, a novel protease from Leishmania braziliensis.Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach.The effect of 17β-estradiol on the expression of dipeptidyl peptidase III and heme oxygenase 1 in liver of CBA/H mice.

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P2860

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.

http://www.wikidata.org/entity/Q36745578

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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type

label

Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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prefLabel

Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

@ast

Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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0008-5472.CAN-12-4400

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Cancer Research

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Proteomic analysis of ubiquiti ...... t inhibit NRF2 ubiquitination.

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Bridgid E Hast

http://www.w3.org/2001/XMLSchema#string

Dennis Goldfarb

http://www.w3.org/2001/XMLSchema#string

Feng Yan

http://www.w3.org/2001/XMLSchema#string

Kathleen M Mulvaney

http://www.w3.org/2001/XMLSchema#string

Michael A Hast

http://www.w3.org/2001/XMLSchema#string

Michael B Major

http://www.w3.org/2001/XMLSchema#string

Priscila F Siesser

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P2860

The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair

Identification and characterization of a novel component of the human minichromosome maintenance complex

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.

Interactions of the human MCM-BP protein with MCM complex components and Dbf4

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

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2199-2210

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scholarly article

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10.1158/0008-5472.CAN-12-4400

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7

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73

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2013-02-04T00:00:00Z

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23382044

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protein ubiquitination

P932

3618590

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