Design and synthesis of chiral alpha,alpha-disubstituted amino acids and conformational study of their oligopeptides.
about
Building Bridges: Biocatalytic C–C-Bond Formation toward Multifunctional ProductsEngineered L-serine hydroxymethyltransferase from Streptococcus thermophilus for the synthesis of α,α-dialkyl-α-amino acidsBiosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbonSynthesis of Boc-protected bicycloproline.Recent Progress on the Stereoselective Synthesis of Cyclic Quaternary alpha-Amino Acids.Gold(I)-catalyzed diastereo- and enantioselective 1,3-dipolar cycloaddition and Mannich reactions of azlactones.Novel synthesis of various orthogonally protected Cα-methyllysine analogues and biological evaluation of a vapreotide analogue containing (S)-α-methyllysine.Effects of peptides derived from terminal modifications of the aβ central hydrophobic core on aβ fibrillization.Stereoselective Synthesis of Quaternary Proline Analogues.Converting disulfide bridges in native peptides to stable methylene thioacetals.Handedness preference and switching of peptide helices. Part II: Helices based on noncoded α-amino acids.Advances in the synthesis of α-quaternary α-ethynyl α-amino acids.Asymmetric synthesis of quaternary aryl amino acid derivatives via a three-component aryne coupling reaction.Control of diastereoselectivity for iridium-catalyzed allylation of a prochiral nucleophile with a phosphate counterion.Exploring the consequences of a representative "disallowed" conformation of Aib on a 3₁₀-helical fold.Thermodynamic and Structural Impact of α,α-Dialkylated Residue Incorporation in a β-Hairpin Peptide.Enantioselective radical addition to ketimines: a synthetic route towards α,α-disubstituted α-amino acids.Synthesis of new Calpha-tetrasubstituted alpha-amino acids.Multiple, consecutive, fully-extended 2.0₅-helix peptide conformation.Catalytic asymmetric synthesis of spirocyclic azlactones by a double Michael-addition approach.The 2.0₅-helix in hetero-oligopeptides entirely composed of C(α,α)-disubstituted glycines with both side chains longer than methyls.Diastereomeric Right- and Left-Handed Helical Structures with Fourteen (R)-Chiral Centers.Asymmetric Synthesis of Less Accessible α-Tertiary Amines from Alkynyl Z-Ketimines.Copper-catalyzed asymmetric alkynylation of cyclic N-sulfonyl ketimines.Low pH-triggering changes in peptide secondary structures.Peptide Secondary Structures as Molecular SwitchesChiral, fully extended helical peptides
P2860
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P2860
Design and synthesis of chiral alpha,alpha-disubstituted amino acids and conformational study of their oligopeptides.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Design and synthesis of chiral ...... study of their oligopeptides.
@en
type
label
Design and synthesis of chiral ...... study of their oligopeptides.
@en
prefLabel
Design and synthesis of chiral ...... study of their oligopeptides.
@en
P356
P1476
Design and synthesis of chiral ...... study of their oligopeptides.
@en
P2093
Masakazu Tanaka
P304
P356
10.1248/CPB.55.349
P407
P577
2007-03-01T00:00:00Z