Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide. - Wikidata - wikimedia - TriplyDB

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

http://www.wikidata.org/entity/Q36749396

about

Cell interactions and patterned intercalations shape and link epithelial tubes in C. elegans Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines Novel genetic targets in endometrial cancer.DNA-binding small molecules as inhibitors of transcription factors.Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.Systematic synthetic and biophysical development of mixed sequence DNA binding agents.Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice.EVI1 Interferes with Myeloid Maturation via Transcriptional Repression of Cebpa, via Binding to Two Far Downstream Regulatory Elements.Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines.Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth.EVI-1 modulates leukemogenic potential and apoptosis sensitivity in human acute lymphoblastic leukemia.MDS1 and EVI1 complex locus (MECOM): a novel candidate gene for hereditary hematological malignancies.EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription ELF3, ELF5, EHF and SPDEF Transcription Factors in Tissue Homeostasis and Cancer Suppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expression

P2860

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P2860

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

http://www.wikidata.org/entity/Q36749396

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

@en

type

label

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

@en

prefLabel

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

@en

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P1476

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

@en

P2093

Archibald S Perkins

http://www.w3.org/2001/XMLSchema#string

Charles A Wuertzer

http://www.w3.org/2001/XMLSchema#string

Daniel A Harki

http://www.w3.org/2001/XMLSchema#string

Géraldine Sicot

http://www.w3.org/2001/XMLSchema#string

John Wheeler

http://www.w3.org/2001/XMLSchema#string

Katy A Muzikar

http://www.w3.org/2001/XMLSchema#string

Kimberly Lezon-Geyda

http://www.w3.org/2001/XMLSchema#string

Marion Vogel

http://www.w3.org/2001/XMLSchema#string

Xiaohui Cui

http://www.w3.org/2001/XMLSchema#string

Yi Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis

Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

Structural basis for G.C recognition in the DNA minor groove

A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA

Sequencing end-labeled DNA with base-specific chemical cleavages

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling

P304

10431-10441

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scholarly article

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10.1021/BI200962U

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48

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50

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Daniel A. Stolper

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2011-11-10T00:00:00Z

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51757301

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22039883

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3619939

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