Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins
about
Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elementsMechanism of c-myc regulation by c-Myb in different cell lineages.Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoterX-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.Interferon gamma response region in the promoter of the human DPA gene.The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.The MHC class II E beta promoter: a complex arrangement of positive and negative elements determines B cell and interferon-gamma (IFN-gamma) regulated expression.Regulatory factor-X binding to mutant HLA-DRA promoter sequencesImportance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants.YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.The myc intron-binding polypeptide associates with RFX1 in vivo and binds to the major histocompatibility complex class II promoter region, to the hepatitis B virus enhancer, and to regulatory regions of several distinct viral genes.Affinity enrichment and functional characterization of TRAX1, a novel transcription activator and X1-sequence-binding protein of HLA-DRAThe same CCAAT box-binding factor binds to the promoter of two coordinately regulated major histocompatibility complex class II genes.Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors.Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes.In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma.Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors.Transcriptional regulation of HLA class-II genes.I-E transgenic mice: a model system to dissect the regulation and function of MHC class II genes in vivo.The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein.An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DR alpha promoter and activation by SV40 T-antigen.Oct-1 maintains an intermediate, stable state of HLA-DRA promoter repression in Rb-defective cells: an Oct-1-containing repressosome that prevents NF-Y binding to the HLA-DRA promoter.Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.Identification of the transcription factors NF-YA and NF-YB as factors A and B that bound to the promoter of the major histocompatibility complex class II gene I-A beta.Human chromosome 12 is required for optimal interactions between Tat and TAR of human immunodeficiency virus type 1 in rodent cells.B-cell factor 1 is required for optimal expression of the DRA promoter in B cells.Current concepts in DRA gene regulation.The presence of a DNA binding complex correlates with E beta class II MHC gene expressionThe transcriptional regulation of human aldehyde dehydrogenase I gene. The structural and functional analysis of the promoter.The mouse Eb meiotic recombination hotspot contains a tissue-specific transcriptional enhancer.Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y.Functional analysis of cis-linked regulatory sequences in the HLA DRA promoter by transcription in vitro.
P2860
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P2860
Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Class II box consensus sequenc ...... eraction with nuclear proteins
@en
type
label
Class II box consensus sequenc ...... eraction with nuclear proteins
@en
prefLabel
Class II box consensus sequenc ...... eraction with nuclear proteins
@en
P2093
P2860
P356
P1476
Class II box consensus sequenc ...... eraction with nuclear proteins
@en
P2093
P2860
P356
10.1128/MCB.9.1.50
P407
P577
1989-01-01T00:00:00Z