MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.
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MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cellsFunctional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Mucin-Type O-Glycosylation in Gastric CarcinogenesisMolecular alterations in gastric cancer with special reference to the early-onset subtypeApplications of aptamers in targeted imaging: state of the artIntracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle FormulationCharacterization of the MUC1-C Cytoplasmic Domain as a Cancer TargetPersonalized characterization of diseases using sample-specific networksCooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cellsNetwork-based inference framework for identifying cancer genes from gene expression dataHEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.MUC1-C activates BMI1 in human cancer cells.Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells.Protein mislocalization: mechanisms, functions and clinical applications in cancer.A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance.Targeting the oncogenic MUC1-C protein inhibits mutant EGFR-mediated signaling and survival in non-small cell lung cancer cellsMUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cellsThe role of the small GTPase Rab31 in cancer.MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLCRole of the unfolded protein response in regulating the mucin-dependent filamentous-growth mitogen-activated protein kinase pathway.Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C.Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathwayAberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ.Robust meta-analysis of gene expression using the elastic net.Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.MUC1-C activates the TAK1 inflammatory pathway in colon cancerLoss of Core 1-derived O-Glycans Decreases Breast Cancer Development in MiceTargeted nanoparticles for image-guided treatment of triple-negative breast cancer: clinical significance and technological advancesMuc1 promotes migration and lung metastasis of melanoma cells.Muc-1 promotes migration and invasion of oral squamous cell carcinoma cells via PI3K-Akt signalingSystematic Identification and Assessment of Therapeutic Targets for Breast Cancer Based on Genome-Wide RNA Interference TranscriptomesPathobiological implications of mucin glycans in cancer: Sweet poison and novel targets.Anti-MUC1 Antibody in Nipple Aspirate Fluids Correlates with Tumor Aggressiveness in Breast Cancer: A Feasibility Study.Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphomaInhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells.Expression of underglycosylated MUC1 antigen in cancerous and adjacent normal breast tissues.Plasma levels and diagnostic utility of VEGF, MMP-9, and TIMP-1 in the diagnosis of patients with breast cancer.Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas.Identification of Potential Drug Targets in Cancer Signaling Pathways using Stochastic Logical Models.
P2860
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P2860
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
MUC1-C oncoprotein as a target ...... ys and therapeutic approaches.
@en
type
label
MUC1-C oncoprotein as a target ...... ys and therapeutic approaches.
@en
prefLabel
MUC1-C oncoprotein as a target ...... ys and therapeutic approaches.
@en
P2860
P356
P1433
P1476
MUC1-C oncoprotein as a target ...... ys and therapeutic approaches.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.158
P407
P577
2012-05-14T00:00:00Z