SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.Computational insights into the binding mechanism of antagonists with neuropeptide B/W receptor 1.

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P2860

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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type

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label

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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prefLabel

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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P1476

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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Edward Roberts

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Hugh Rosen

http://www.w3.org/2001/XMLSchema#string

Mariangela Urbano

http://www.w3.org/2001/XMLSchema#string

Marie-Therese Schaeffer

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Miguel Guerrero

http://www.w3.org/2001/XMLSchema#string

Steven Brown

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P2860

The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain

A role for neuropeptide W in the regulation of feeding behavior

Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8

Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory

Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8

Schwann cell overexpression of the GPR7 receptor in inflammatory and painful neuropathies

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity

A single nucleotide polymorphism of the neuropeptide B/W receptor-1 gene influences the evaluation of facial expressions.

Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7).

Analgesic neuropeptide W suppresses seizures in the brain revealed by rational repositioning and peptide engineering.

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scholarly article

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10.1016/J.BMCL.2012.12.030

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English

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2012-12-20T00:00:00Z

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23287738

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3621982

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SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

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P2860

P2860

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists.

description

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932