ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
about
Two-step ATP-driven opening of cohesin headEukaryotic Rad50 functions as a rod-shaped dimer.Functions and regulation of the MRX complex at DNA double-strand breaks.DNA binding to SMC ATPases-trapped for release.Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites.Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Physical and functional interplay between PCNA DNA clamp and Mre11-Rad50 complex from the archaeon Pyrococcus furiosus.Suppressor mutation analysis combined with 3D modeling explains cohesin's capacity to hold and release DNA.
P2860
Q30855484-95504212-134C-4BDD-B987-037DBC2AAFA7Q38992191-5D5CDADC-F5A8-4589-AEC4-C6420019C889Q39208189-0AD9857C-F179-4103-AD0E-8AF7723AF2CFQ39815024-A903EF4C-B137-40FE-B48B-862589977685Q42139576-0BBA2CD5-1711-4641-A0CF-8C172C1777C5Q47863035-57C1FBC6-2044-4B7A-A28B-E3117D13CB38Q50113705-4D566A41-0024-427D-9E53-0F3F5E4736C3Q54980026-1D19676A-F670-466E-8174-D378C9E135D4Q55254792-703DB03F-951E-49B6-A735-952C82C650FAQ55315131-5AF41AFA-2702-46D0-AE0F-A9FB40A1D373
P2860
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@ast
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@en
type
label
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@ast
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@en
prefLabel
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@ast
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@en
P2093
P2860
P356
P1433
P1476
ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
@en
P2093
Ae-Kyoung Kim
Gwanghyun Gwon
Ok-Kyu Song
Sang Eun Lee
Sihyun Sung
Taeyoon Kim
Youngran Kim
P2860
P304
P356
10.15252/EMBJ.201592462
P407
P577
2015-12-30T00:00:00Z