HIV-specific CD8+ T cells from elite controllers are primed for survival.
about
Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects.Levels of CD56+TIM-3- effector CD8 T cells distinguish HIV natural virus suppressors from patients receiving antiretroviral therapy.Frequencies of Gag-restricted T-cell escape "footprints" differ across HIV-1 clades A1 and D chronically infected Ugandans irrespective of host HLA B allelesHigher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers.HIV-specific CD8⁺ T cells and HIV eradicationNormal T-cell activation in elite controllers with preserved CD4+ T-cell countsElite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors.Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.
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P2860
HIV-specific CD8+ T cells from elite controllers are primed for survival.
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2013 nî lūn-bûn
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HIV-specific CD8+ T cells from elite controllers are primed for survival.
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HIV-specific CD8+ T cells from elite controllers are primed for survival.
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label
HIV-specific CD8+ T cells from elite controllers are primed for survival.
@ast
HIV-specific CD8+ T cells from elite controllers are primed for survival.
@en
prefLabel
HIV-specific CD8+ T cells from elite controllers are primed for survival.
@ast
HIV-specific CD8+ T cells from elite controllers are primed for survival.
@en
P2093
P2860
P356
P1433
P1476
HIV-specific CD8+ T cells from elite controllers are primed for survival
@en
P2093
Anju Bansal
John J Shacka
Paul A Goepfert
Sonya L Heath
P2860
P304
P356
10.1128/JVI.02379-12
P407
P577
2013-02-28T00:00:00Z