about
An overview of epigenetics and chemopreventionEnvironmental Epigenetics: Crossroad between Public Health, Lifestyle, and Cancer PreventionA perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomicsResearch progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanismsEnhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for CancerDNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromesThrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylationGenome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing.Widespread and tissue specific age-related DNA methylation changes in mice.Low-dose decitabine-based chemoimmunotherapy for patients with refractory advanced solid tumors: a phase I/II reportLung cancer: a modified epigenome.Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recoveryResistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human.Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromesA DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells.Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesisEpigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic virusesMethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomesDNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission.Histone deacetylase inhibitors in Hodgkin lymphoma.Analyzing the cancer methylome through targeted bisulfite sequencingReactivation of the tumour suppressor RASSF1A in breast cancer by simultaneous targeting of DNA and E2F1 methylation.Intracellular Distribution-based Anticancer Drug Targeting: Exploiting a Lysosomal Acidification Defect Associated with Cancer Cells.Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cellsCurcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.Curcumin modulates DNA methylation in colorectal cancer cells.An integrated approach to uncover driver genes in breast cancer methylation genomes.Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study.An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancerEpigenetic regulation of cancer-associated genes in ovarian cancer.Therapeutic modulation of epigenetic drivers of drug resistance in ovarian cancer.SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation.In silico Identification of SFRP1 as a Hypermethylated Gene in Colorectal Cancers.Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis.5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
DNA methylation as a therapeutic target in cancer.
@ast
DNA methylation as a therapeutic target in cancer.
@en
type
label
DNA methylation as a therapeutic target in cancer.
@ast
DNA methylation as a therapeutic target in cancer.
@en
prefLabel
DNA methylation as a therapeutic target in cancer.
@ast
DNA methylation as a therapeutic target in cancer.
@en
P1476
DNA methylation as a therapeutic target in cancer.
@en
P2093
Jean-Pierre J Issa
P304
P356
10.1158/1078-0432.CCR-06-2076
P407
P577
2007-03-01T00:00:00Z