Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/reductase superfamily.
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Structural basis for substrate specificity in human monomeric carbonyl reductasesReciprocal changes in maternal and fetal metabolism of corticosterone in rat during gestationMolecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases.Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome.Structure of a short-chain dehydrogenase/reductase (SDR) within a genomic island from a clinical strain of Acinetobacter baumannii.The mechanism of enterohepatic circulation in the formation of gallstone disease.MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024.SDR9C7 promotes lymph node metastases in patients with esophageal squamous cell carcinoma.A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2RNA sequencing identifies upregulated kyphoscoliosis peptidase and phosphatidic acid signaling pathways in muscle hypertrophy generated by transgenic expression of myostatin propeptideCharacterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218Crystallization of an atypical short-chain dehydrogenase from Vibrio vulnificus lacking the conserved catalytic tetrad.AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and transSelenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells.Detoxification reactions: relevance to aging.Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone.Enzymes without borders: mobilizing substrates, delivering products.Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.Bacterial degradation of bile salts.Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily.Carbonyl reduction pathways in drug metabolism.Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate.The modulation of carbonyl reductase 1 by polyphenols.The role of carbonyl reductase 1 in drug discovery and development.Mechanisms of tumor cell resistance to the current targeted-therapy agents.Species differences in hepatic biotransformation of the anthelmintic drug flubendazole.Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyreneTranscriptional regulation of human and murine short-chain dehydrogenase/reductases (SDRs) - an in silico approach.Mouse 11β-hydroxysteroid dehydrogenase type 2 for human application: homology modeling, structural analysis and ligand-receptor interaction.Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol.Structure-based conversion of the coenzyme requirement of a short-chain dehydrogenase/reductase involved in bacterial alginate metabolism.Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases.Evolution of 11beta-hydroxysteroid dehydrogenase-type 1 and 11beta-hydroxysteroid dehydrogenase-type 3.Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.Efficient isolation of carbonyl-reducing enzymes using affinity approach with anticancer drug oracin as a specific ligand.Characterization of a newly synthesized carbonyl reductase and construction of a biocatalytic process for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate with high space-time yield.Comparative inhibition of tetrameric carbonyl reductase activity in pig heart cytosol by alkyl 4-pyridyl ketones.Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.Structural functionality, catalytic mechanism modeling and molecular allergenicity of phenylcoumaran benzylic ether reductase, an olive pollen (Ole e 12) allergen.A Catalyst from Burkholderia cenocepacia for Efficient Anti-Prelog's Bioreduction of 3,5-Bis(Trifluoromethyl) Acetophenone.
P2860
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P2860
Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/reductase superfamily.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@ast
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@en
type
label
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@ast
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@en
prefLabel
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@ast
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@en
P2860
P1476
Carbonyl reductases and plurip ...... ogenase/reductase superfamily.
@en
P2093
Edmund Maser
Frank Hoffmann
P2860
P304
P356
10.1080/03602530600969440
P407
P577
2007-01-01T00:00:00Z